Technology Process of C10H8Br3N5O
There total 7 articles about C10H8Br3N5O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: bromine; copper(ll) bromide / acetonitrile / 1 h / 50 °C
1.2: 0.5 h
2.1: sodium azide / N,N-dimethyl-formamide
3.1: sodium hydroxide / ethanol / 3 h / 85 °C
4.1: tert.-butylnitrite / tetrahydrofuran / 3 h / 50 °C
5.1: triethylamine; trifluoroacetic anhydride / dichloromethane / 2 h / 20 °C
6.1: hydroxylamine hydrochloride; potassium carbonate / ethanol / 16 h / 20 °C
With
sodium azide; tert.-butylnitrite; hydroxylamine hydrochloride; bromine; potassium carbonate; triethylamine; trifluoroacetic anhydride; sodium hydroxide; copper(ll) bromide;
In
tetrahydrofuran; ethanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.bmcl.2011.08.073
- Guidance literature:
-
With
hydroxylamine hydrochloride; potassium carbonate;
In
ethanol;
at 20 ℃;
for 16h;
DOI:10.1016/j.bmcl.2011.08.073
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydroxide / ethanol / 3 h / 85 °C
2: tert.-butylnitrite / tetrahydrofuran / 3 h / 50 °C
3: triethylamine; trifluoroacetic anhydride / dichloromethane / 2 h / 20 °C
4: hydroxylamine hydrochloride; potassium carbonate / ethanol / 16 h / 20 °C
With
tert.-butylnitrite; hydroxylamine hydrochloride; potassium carbonate; triethylamine; trifluoroacetic anhydride; sodium hydroxide;
In
tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1016/j.bmcl.2011.08.073
