S-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-(1<*>1)-(2R,3R,4E)-3-O-benzoyl-2-dichloroacetamido-4-octadecen-1-thiol

Base Information

Chemical Name:S-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-(1<*>1)-(2R,3R,4E)-3-O-benzoyl-2-dichloroacetamido-4-octadecen-1-thiol
CAS No.:173067-93-1
Molecular Formula:C₄₁H₅₉Cl₂NO₁₂S
Molecular Weight:860.891
Hs Code.:

Synonyms:S-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-(1<*>1)-(2R,3R,4E)-3-O-benzoyl-2-dichloroacetamido-4-octadecen-1-thiol

Suppliers and Price of S-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-(1<*>1)-(2R,3R,4E)-3-O-benzoyl-2-dichloroacetamido-4-octadecen-1-thiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of S-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-(1<*>1)-(2R,3R,4E)-3-O-benzoyl-2-dichloroacetamido-4-octadecen-1-thiol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of S-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-(1<*>1)-(2R,3R,4E)-3-O-benzoyl-2-dichloroacetamido-4-octadecen-1-thiol

There total 7 articles about S-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-(1<*>1)-(2R,3R,4E)-3-O-benzoyl-2-dichloroacetamido-4-octadecen-1-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 40591-65-9
2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl isothiouronium bromide

: 173067-92-0
Benzoic acid (E)-(R)-1-[(R)-1-(2,2-dichloro-acetylamino)-2-iodo-ethyl]-hexadec-2-enyl ester

: 173067-93-1
S-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-(1<*>1)-(2R,3R,4E)-3-O-benzoyl-2-dichloroacetamido-4-octadecen-1-thiol

Guidance literature:: With sodium acetate; potassium carbonate; In methanol; acetone; at 20 ℃; for 6h;
DOI:10.1016/0008-6215(95)00189-Z

Reference yield:

: 123-78-4
(2S,3R,4E)-2-amino-4-octadecene-1,3-diol

: 173067-93-1
S-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-(1<*>1)-(2R,3R,4E)-3-O-benzoyl-2-dichloroacetamido-4-octadecen-1-thiol

Guidance literature:: Multi-step reaction with 7 steps

1: N,N-diisopropylethylamine, aliquots / methanol; CH₂Cl₂

2: 95 percent / Et₃N, N,N-dimethylaminopyridine / CH₂Cl₂; tetrahydrofuran / 7 h / Ambient temperature

3: 96 percent / pyridine / Ambient temperature

4: 70 percent / tetrabutylammonium fluoride / tetrahydrofuran / 35 °C

5: 90 percent / pyridine / 0 °C

6: 94 percent / sodium iodide / acetone / 7 h / 60 °C

7: 70 percent / sodium acetate, potassium carbonate / acetone; methanol / 6 h / 20 °C

With pyridine; dmap; aliquots; tetrabutyl ammonium fluoride; sodium acetate; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; sodium iodide; In tetrahydrofuran; methanol; dichloromethane; acetone;
DOI:10.1016/0008-6215(95)00189-Z

Reference yield:

: 80692-62-2
N-dichloroacetylsphingosine

: 173067-93-1
S-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-(1<*>1)-(2R,3R,4E)-3-O-benzoyl-2-dichloroacetamido-4-octadecen-1-thiol

Guidance literature:: Multi-step reaction with 6 steps

1: 95 percent / Et₃N, N,N-dimethylaminopyridine / CH₂Cl₂; tetrahydrofuran / 7 h / Ambient temperature

2: 96 percent / pyridine / Ambient temperature

3: 70 percent / tetrabutylammonium fluoride / tetrahydrofuran / 35 °C

4: 90 percent / pyridine / 0 °C

5: 94 percent / sodium iodide / acetone / 7 h / 60 °C

6: 70 percent / sodium acetate, potassium carbonate / acetone; methanol / 6 h / 20 °C

With pyridine; dmap; tetrabutyl ammonium fluoride; sodium acetate; potassium carbonate; triethylamine; sodium iodide; In tetrahydrofuran; methanol; dichloromethane; acetone;
DOI:10.1016/0008-6215(95)00189-Z