Technology Process of 1-(3,3-dimethyl-2-phenylcyclopent-1-en-1-yl)-4-fluorobenzene
There total 2 articles about 1-(3,3-dimethyl-2-phenylcyclopent-1-en-1-yl)-4-fluorobenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
bis(4-fluorophenyl)iodonium hexafluorophosphate;
With
copper(II) bis(trifluoromethanesulfonate);
at 80 ℃;
for 1h;
Inert atmosphere;
Sealed tube;
Schlenk technique;
(5-methylhex-1-yn-1-yl)benzene;
In
1,2-dichloro-ethane;
at 60 ℃;
for 12h;
Inert atmosphere;
Sealed tube;
Schlenk technique;
DOI:10.1021/ol501655g
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium hexafluorophosphate / acetonitrile / 24 h / Inert atmosphere; Sealed tube
2.1: copper(II) bis(trifluoromethanesulfonate) / 1 h / 80 °C / Inert atmosphere; Sealed tube; Schlenk technique
2.2: 12 h / 60 °C / Inert atmosphere; Sealed tube; Schlenk technique
With
potassium hexafluorophosphate; copper(II) bis(trifluoromethanesulfonate);
In
acetonitrile;
DOI:10.1021/ol501655g
