N-allyl-N-benzyl 2-hexynamide

Base Information

• Chemical Name: N-allyl-N-benzyl 2-hexynamide
• CAS No.: 151418-22-3
• Molecular Formula: C₁₆H₁₉NO
• Molecular Weight: 241.333
• Mol file: 151418-22-3.mol

Synonyms:N-allyl-N-benzyl 2-hexynamide

Chemical Property of N-allyl-N-benzyl 2-hexynamide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of N-allyl-N-benzyl 2-hexynamide

There total 1 articles about N-allyl-N-benzyl 2-hexynamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

Allylbenzylamine (4383-22-6) + hex-2-ynoic acid (764-33-0) → N-allyl-N-benzyl 2-hexynamide (151418-22-3)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 20h; Ambient temperature;

DOI:10.1016/0040-4020(95)00035-7

Reference yield: 60.0%

N-allyl-N-benzyl 2-hexynamide (151418-22-3) → (E,E)-N-allylbenzylhexa-2,4-dienamide (85738-11-0)

Guidance literature:

With tributylphosphine; In toluene; at 110 ℃; for 24h;

Reference yield: 43.0%

1-chloro-4-iodo-1,1,2,2,3,3,4,4-octafluorobutane (5848-38-4) + N-allyl-N-benzyl 2-hexynamide (151418-22-3) → N-benzyl-N-(4'-(ω-chlorooctafluorobutyl)-2-iodopropyl) 2-hexynamide + 1-benzyl-4-(4'-chlorooctafluorobutylmethyl)-3-(E)-(1'-iodobutylidene)-2(3H)-dihydropyrrolidone

Guidance literature:

With sodium dithionite; sodium hydrogencarbonate; In water; acetonitrile; at 10 - 15 ℃;

DOI:10.1016/0040-4020(95)00035-7

upstream raw materials:

Allylbenzylamine

hex-2-ynoic acid

Downstream raw materials:

(E,E)-N-allylbenzylhexa-2,4-dienamide