1-methyl(diphenyl)silyl-2,3,5-triphenylbenzene

Base Information

• Chemical Name: 1-methyl(diphenyl)silyl-2,3,5-triphenylbenzene
• CAS No.: 1438771-21-1
• Molecular Formula: C₃₇H₃₀Si
• Molecular Weight: 502.731
• Mol file: 1438771-21-1.mol

Synonyms:1-methyl(diphenyl)silyl-2,3,5-triphenylbenzene

Chemical Property of 1-methyl(diphenyl)silyl-2,3,5-triphenylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-methyl(diphenyl)silyl-2,3,5-triphenylbenzene

There total 6 articles about 1-methyl(diphenyl)silyl-2,3,5-triphenylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

iodobenzene (591-50-4) + C29H34O2Si3 (1438771-60-8) → 1-methyl(diphenyl)silyl-2,3,5-triphenylbenzene (1438771-21-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutyl ammonium fluoride; silver(l) oxide; In tetrahydrofuran; at 65 ℃; for 16h; Inert atmosphere;

DOI:10.1021/ol4010883

Reference yield:

(E)-1-iodo-1-methyl(diphenyl)silyl-2-phenylethene (1438768-98-9) → 1-methyl(diphenyl)silyl-2,3,5-triphenylbenzene (1438771-21-1)

Guidance literature:

Multi-step reaction with 4 steps

1: palladium diacetate; N-ethyl-N,N-diisopropylamine / 24 h / 30 °C

2: lithium aluminium tetrahydride / 1,4-dioxane / 18 h / 80 °C / Inert atmosphere

3: palladium 10% on activated carbon / water; pentane / 6 h / 20 °C / Inert atmosphere

4: tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutyl ammonium fluoride; silver(l) oxide / tetrahydrofuran / 16 h / 65 °C / Inert atmosphere

With lithium aluminium tetrahydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; tetrabutyl ammonium fluoride; palladium diacetate; N-ethyl-N,N-diisopropylamine; silver(l) oxide; In tetrahydrofuran; 1,4-dioxane; water; pentane; 4: |Hiyama Coupling;

DOI:10.1021/ol4010883

Reference yield:

1,3,5-tris[methyl(diphenyl)silyl]-2-phenylbenzene (1438770-56-9) → 1-methyl(diphenyl)silyl-2,3,5-triphenylbenzene (1438771-21-1)

Guidance literature:

Multi-step reaction with 3 steps

1: lithium aluminium tetrahydride / 1,4-dioxane / 18 h / 80 °C / Inert atmosphere

2: palladium 10% on activated carbon / water; pentane / 6 h / 20 °C / Inert atmosphere

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutyl ammonium fluoride; silver(l) oxide / tetrahydrofuran / 16 h / 65 °C / Inert atmosphere

With lithium aluminium tetrahydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; tetrabutyl ammonium fluoride; silver(l) oxide; In tetrahydrofuran; 1,4-dioxane; water; pentane; 3: |Hiyama Coupling;

DOI:10.1021/ol4010883

upstream raw materials:

(E)-1-iodo-1-methyl(diphenyl)silyl-2-phenylethene

chloromethyldiphenylsilane

1,3,5-tris[methyl(diphenyl)silyl]-2-phenylbenzene

1-(methyldiphenylsilyl)-2-phenylethyne