ethyl {4,5,7-tri-O-benzyl-2,3-dehydro-8-O-[ethyl (4,5,7,8-tetra-O-benzyl-3-deoxy-3-iodo-α-D-manno-2-octulopyranosyl)onate]-α-D-manno-2-octulopyranosyl}onate

Base Information

• Chemical Name: ethyl {4,5,7-tri-O-benzyl-2,3-dehydro-8-O-[ethyl (4,5,7,8-tetra-O-benzyl-3-deoxy-3-iodo-α-D-manno-2-octulopyranosyl)onate]-α-D-manno-2-octulopyranosyl}onate
• CAS No.: 880883-43-2
• Molecular Formula: C₆₉H₇₃IO₁₄
• Molecular Weight: 1253.23
• Mol file: 880883-43-2.mol

Synonyms:ethyl {4,5,7-tri-O-benzyl-2,3-dehydro-8-O-[ethyl (4,5,7,8-tetra-O-benzyl-3-deoxy-3-iodo-α-D-manno-2-octulopyranosyl)onate]-α-D-manno-2-octulopyranosyl}onate

Chemical Property of ethyl {4,5,7-tri-O-benzyl-2,3-dehydro-8-O-[ethyl (4,5,7,8-tetra-O-benzyl-3-deoxy-3-iodo-α-D-manno-2-octulopyranosyl)onate]-α-D-manno-2-octulopyranosyl}onate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl {4,5,7-tri-O-benzyl-2,3-dehydro-8-O-[ethyl (4,5,7,8-tetra-O-benzyl-3-deoxy-3-iodo-α-D-manno-2-octulopyranosyl)onate]-α-D-manno-2-octulopyranosyl}onate

There total 1 articles about ethyl {4,5,7-tri-O-benzyl-2,3-dehydro-8-O-[ethyl (4,5,7,8-tetra-O-benzyl-3-deoxy-3-iodo-α-D-manno-2-octulopyranosyl)onate]-α-D-manno-2-octulopyranosyl}onate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

ethyl 4,5,7-tri-O-benzyl-2,3-di-deoxy-8-O-[ethyl (4,5,7,8-tetra-O-benzyl-3-deoxy-3-iodo-α-D-manno-2-octulopyranosyl)onate]-α-D-manno-2-octonate 1-S-oxido-1,3-propylene dithioketal → ethyl {4,5,7-tri-O-benzyl-2,3-dehydro-8-O-[ethyl (4,5,7,8-tetra-O-benzyl-3-deoxy-3-iodo-α-D-manno-2-octulopyranosyl)onate]-α-D-manno-2-octulopyranosyl}onate (880883-43-2)

Guidance literature:

With oxalyl dichloride; 4 A molecular sieve; silver trifluoromethanesulfonate; In dichloromethane; at -30 - 0 ℃;

DOI:10.1002/anie.200503299

Reference yield: 80.0%

tetradecyl 2,3,4-triO-benzyl-β-D-glucopyranoside (880883-32-9) + ethyl {4,5,7-tri-O-benzyl-2,3-dehydro-8-O-[ethyl (4,5,7,8-tetra-O-benzyl-3-deoxy-3-iodo-α-D-manno-2-octulopyranosyl)onate]-α-D-manno-2-octulopyranosyl}onate (880883-43-2) → tetradecyl 2,3,4-tri-O-benzyl-6-O-(ethyl {4,5,7-tri-O-benzyl-8-O-[ethyl (4,5,7,8-tetra-O-benzyl-3-deoxy-3-iodo-α-D-manno-2-octulopyranosyl)onate]-3-deoxy-3-iodo-α-D-manno-2-octulopyranosyl}onate)-β-D-glucopyranoside

Guidance literature:

With N-iodo-succinimide; trifluorormethanesulfonic acid; 4 A molecular sieve; In dichloromethane; at -50 - 20 ℃;

DOI:10.1002/anie.200503299

Reference yield: 68.0%

ethyl 4,5,7-tri-O-benzyl-3-deoxy-D-manno-2-octonate 1-S-oxido-1,3-propylene dithioketal (880883-41-0) + ethyl {4,5,7-tri-O-benzyl-2,3-dehydro-8-O-[ethyl (4,5,7,8-tetra-O-benzyl-3-deoxy-3-iodo-α-D-manno-2-octulopyranosyl)onate]-α-D-manno-2-octulopyranosyl}onate (880883-43-2) → C103H114I2O22S2

Guidance literature:

With N-iodo-succinimide; trifluorormethanesulfonic acid; 4 A molecular sieve; In dichloromethane; at -50 - -20 ℃;

DOI:10.1002/anie.200503299