7,12-dimethyl-1,2-dihydrotetraphene

Base Information

• Chemical Name: 7,12-dimethyl-1,2-dihydrotetraphene
• CAS No.: 72648-44-3
• Molecular Formula: C₂₀H₁₈
• Molecular Weight: 258.363
• Mol file: 72648-44-3.mol

Synonyms:1,2-Dihydro-7,12-dimethylbenz[a]anthracene

Chemical Property of 7,12-dimethyl-1,2-dihydrotetraphene

Chemical Property:

• Vapor Pressure: 8.02E-08mmHg at 25°C
• Boiling Point: 448.7°Cat760mmHg
• Flash Point: 218.9°C
• Density: 1.121g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7,12-dimethyl-1,2-dihydrotetraphene

There total 4 articles about 7,12-dimethyl-1,2-dihydrotetraphene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

1,2-dihydro-7,12-dihydroxy-7,12-dimethylbenzanthracene (118658-59-6) → 1,2-dihydro-7,12-dimethylbenzanthracene (72648-44-3)

Guidance literature:

With lithium aluminium tetrahydride; titanium(III) chloride; In tetrahydrofuran; 1.) 0 deg C, 15 min, 2.) reflux, 3 h;

DOI:10.1021/jo00265a025

Reference yield:

1,2,3,4-tetrahydrobenzanthracen-4,7,12-trione 4-tosylhydrazone (72648-41-0) → 1,2-dihydro-7,12-dimethylbenzanthracene (72648-44-3)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrahydrofuran; diethyl ether / 16 h / Ambient temperature

2: 48percent HI / methanol / 0.17 h

3: NaBH₄ / aq. ethanol / 2 h / Ambient temperature

With sodium tetrahydroborate; hydrogen iodide; In tetrahydrofuran; methanol; diethyl ether; ethanol;

DOI:10.1021/jm00177a013

Reference yield:

7-Iodomethyl-12-methyl-1,2-dihydro-benzo[a]anthracene → 1,2-dihydro-7,12-dimethylbenzanthracene (72648-44-3)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 2h; Yield given; Ambient temperature;

DOI:10.1021/jm00177a013

upstream raw materials:

1,2-dihydro-7,12-dihydroxy-7,12-dimethylbenzanthracene

1,2,3,4-tetrahydrobenzanthracen-4,7,12-trione 4-tosylhydrazone

1,2,3,4-tetrahydrobenzanthracene-7,12-dione