Technology Process of 1,2-dihydroxy-3,5-dimethoxybenzene
There total 10 articles about 1,2-dihydroxy-3,5-dimethoxybenzene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
2.1: 32 percent / K2CO3 / dimethylformamide / 72 h / 80 °C
3.1: 100 percent / K2CO3 / dimethylformamide / 3 h / 0 °C
4.1: 97 percent / DIBAH / CH2Cl2 / 3 h / -78 °C
5.1: 76 percent / PCC / CH2Cl2 / 2 h / 20 °C
6.1: 30 percent aq. hydrogen peroxide; phenylselenic acid / CH2Cl2 / 48 h / 20 °C
6.2: KOH / methanol / 0.5 h / 20 °C
7.1: KOH / dimethylsulfoxide / 3 h / 20 °C
8.1: 100 percent / hydrogen / 20 percent Pd(OH)2/C / methanol / 18 h / 20 °C
With
potassium hydroxide; phenylselenate; hydrogen; dihydrogen peroxide; diisobutylaluminium hydride; potassium carbonate; pyridinium chlorochromate;
palladium dihydroxide;
In
methanol; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
1.1: Esterification / 2.1: Condensation / 3.1: Methylation / 4.1: Reduction / 5.1: Oxidation / 6.1: Oxidation / 6.2: Hydrolysis / 7.1: Methylation / 8.1: Hydrogenolysis;
DOI:10.1016/S0040-4039(00)00812-1
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 32 percent / K2CO3 / dimethylformamide / 72 h / 80 °C
2.1: 100 percent / K2CO3 / dimethylformamide / 3 h / 0 °C
3.1: 97 percent / DIBAH / CH2Cl2 / 3 h / -78 °C
4.1: 76 percent / PCC / CH2Cl2 / 2 h / 20 °C
5.1: 30 percent aq. hydrogen peroxide; phenylselenic acid / CH2Cl2 / 48 h / 20 °C
5.2: KOH / methanol / 0.5 h / 20 °C
6.1: KOH / dimethylsulfoxide / 3 h / 20 °C
7.1: 100 percent / hydrogen / 20 percent Pd(OH)2/C / methanol / 18 h / 20 °C
With
potassium hydroxide; phenylselenate; hydrogen; dihydrogen peroxide; diisobutylaluminium hydride; potassium carbonate; pyridinium chlorochromate;
palladium dihydroxide;
In
methanol; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
1.1: Condensation / 2.1: Methylation / 3.1: Reduction / 4.1: Oxidation / 5.1: Oxidation / 5.2: Hydrolysis / 6.1: Methylation / 7.1: Hydrogenolysis;
DOI:10.1016/S0040-4039(00)00812-1