1-Phenyl-5-((2E,9Z)-12,12,12-trifluoro-7,7-dimethyl-11-triethylsilanyloxy-11-trifluoromethyl-dodeca-2,9-diene-1-sulfonyl)-1H-tetrazole

Base Information

Chemical Name:1-Phenyl-5-((2E,9Z)-12,12,12-trifluoro-7,7-dimethyl-11-triethylsilanyloxy-11-trifluoromethyl-dodeca-2,9-diene-1-sulfonyl)-1H-tetrazole
CAS No.:332097-85-5
Molecular Formula:C₂₈H₄₀F₆N₄O₃SSi
Molecular Weight:654.793
Hs Code.:

Synonyms:1-Phenyl-5-((2E,9Z)-12,12,12-trifluoro-7,7-dimethyl-11-triethylsilanyloxy-11-trifluoromethyl-dodeca-2,9-diene-1-sulfonyl)-1H-tetrazole

Suppliers and Price of 1-Phenyl-5-((2E,9Z)-12,12,12-trifluoro-7,7-dimethyl-11-triethylsilanyloxy-11-trifluoromethyl-dodeca-2,9-diene-1-sulfonyl)-1H-tetrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-Phenyl-5-((2E,9Z)-12,12,12-trifluoro-7,7-dimethyl-11-triethylsilanyloxy-11-trifluoromethyl-dodeca-2,9-diene-1-sulfonyl)-1H-tetrazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-Phenyl-5-((2E,9Z)-12,12,12-trifluoro-7,7-dimethyl-11-triethylsilanyloxy-11-trifluoromethyl-dodeca-2,9-diene-1-sulfonyl)-1H-tetrazole

There total 8 articles about 1-Phenyl-5-((2E,9Z)-12,12,12-trifluoro-7,7-dimethyl-11-triethylsilanyloxy-11-trifluoromethyl-dodeca-2,9-diene-1-sulfonyl)-1H-tetrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 86-93-1
1-Phenyl-1H-tetrazole-5-thiol

: 332097-81-1
(2E,9Z)-12,12,12-trifluoro-7,7-dimethyl-11-triethylsilanyloxy-11-trifluoromethyl-dodeca-2,9-dien-1-ol

: (Z)-12,12,12-Trifluoro-7,7-dimethyl-11-triethylsilanyloxy-11-trifluoromethyl-dodeca-1,9-dien-3-ol

: 332097-85-5
1-Phenyl-5-((2E,9Z)-12,12,12-trifluoro-7,7-dimethyl-11-triethylsilanyloxy-11-trifluoromethyl-dodeca-2,9-diene-1-sulfonyl)-1H-tetrazole

Guidance literature:: 1-Phenyl-1H-tetrazole-5-thiol; (2E,9Z)-12,12,12-trifluoro-7,7-dimethyl-11-triethylsilanyloxy-11-trifluoromethyl-dodeca-2,9-dien-1-ol; With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 ℃; for 1.5h;

With ammonium heptamolybdate; dihydrogen peroxide; In ethanol; at 22 ℃; for 10h;
DOI:10.1016/S0040-4020(00)01035-8

Reference yield:

: 141-79-7
4-methyl-pent-3-en-2-one

: 332097-85-5
1-Phenyl-5-((2E,9Z)-12,12,12-trifluoro-7,7-dimethyl-11-triethylsilanyloxy-11-trifluoromethyl-dodeca-2,9-diene-1-sulfonyl)-1H-tetrazole

Guidance literature:: Multi-step reaction with 9 steps

1.1: Mg; I₂ / tetrahydrofuran / 3.5 h / Heating

1.2: CuI / tetrahydrofuran / 1 h / -20 °C

2.1: diisopropylamine; n-BuLi; diethyl chlorophosphate / tetrahydrofuran / 4.5 h / -78 - 20 °C

2.2: diisopropylamine; n-BuLi / tetrahydrofuran / 2 h / -78 °C

2.3: 66.82 g / tetrahydrofuran / 0.5 h / -78 °C

3.1: H₂ / Pd/CaCO₃/Pb / various solvent(s) / 1.5 h / 22 °C / 750.06 Torr

4.1: aq. H₂SO₄ / propan-2-ol / 2 h / Heating

5.1: 2.92 g / TEMPO; KBr; NaOCl / NaHCO₃ / CH₂Cl₂; H₂O / 1 h

6.1: 4-dimethylaminopyridine; Et₃N / tetrahydrofuran / 1.5 h / 22 °C

7.1: 96 percent / t-BuOK / toluene / 3 h / -15 - -10 °C

8.1: 100 percent / diisobutyl aluminium hydride / toluene / 3.17 h / -78 °C

9.1: PPh₃; diisopropyl azodicarboxylate / tetrahydrofuran / 1.5 h / 0 °C

9.2: 38 percent / aq. H₂O₂; (NH₄)6Mo₇O₂₄*4H₂O / ethanol / 10 h / 22 °C

With dmap; 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; n-butyllithium; di-isopropyl azodicarboxylate; sulfuric acid; potassium tert-butylate; hydrogen; iodine; diisobutylaluminium hydride; diethyl chlorophosphate; magnesium; triethylamine; diisopropylamine; triphenylphosphine; potassium bromide; Lindlar's catalyst; sodium hydrogencarbonate; In tetrahydrofuran; dichloromethane; water; isopropyl alcohol; toluene; 7.1: Horner reaction;
DOI:10.1016/S0040-4020(00)01035-8

Reference yield:

: 332097-58-2
8-tert-butyloxy-4,4-dimethyl-octan-2-one

: 332097-85-5
1-Phenyl-5-((2E,9Z)-12,12,12-trifluoro-7,7-dimethyl-11-triethylsilanyloxy-11-trifluoromethyl-dodeca-2,9-diene-1-sulfonyl)-1H-tetrazole

Guidance literature:: Multi-step reaction with 8 steps

1.1: diisopropylamine; n-BuLi; diethyl chlorophosphate / tetrahydrofuran / 4.5 h / -78 - 20 °C

1.2: diisopropylamine; n-BuLi / tetrahydrofuran / 2 h / -78 °C

1.3: 66.82 g / tetrahydrofuran / 0.5 h / -78 °C

2.1: H₂ / Pd/CaCO₃/Pb / various solvent(s) / 1.5 h / 22 °C / 750.06 Torr

3.1: aq. H₂SO₄ / propan-2-ol / 2 h / Heating

4.1: 2.92 g / TEMPO; KBr; NaOCl / NaHCO₃ / CH₂Cl₂; H₂O / 1 h

5.1: 4-dimethylaminopyridine; Et₃N / tetrahydrofuran / 1.5 h / 22 °C

6.1: 96 percent / t-BuOK / toluene / 3 h / -15 - -10 °C

7.1: 100 percent / diisobutyl aluminium hydride / toluene / 3.17 h / -78 °C

8.1: PPh₃; diisopropyl azodicarboxylate / tetrahydrofuran / 1.5 h / 0 °C

8.2: 38 percent / aq. H₂O₂; (NH₄)6Mo₇O₂₄*4H₂O / ethanol / 10 h / 22 °C

With dmap; 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; n-butyllithium; di-isopropyl azodicarboxylate; sulfuric acid; potassium tert-butylate; hydrogen; diisobutylaluminium hydride; diethyl chlorophosphate; triethylamine; diisopropylamine; triphenylphosphine; potassium bromide; Lindlar's catalyst; sodium hydrogencarbonate; In tetrahydrofuran; dichloromethane; water; isopropyl alcohol; toluene; 6.1: Horner reaction;
DOI:10.1016/S0040-4020(00)01035-8