BIPHENYL-2,2'-DIMETHANAMINE

Base Information

• Chemical Name: BIPHENYL-2,2'-DIMETHANAMINE
• CAS No.: 70898-14-5
• Molecular Formula: C₁₄H₁₆N₂
• Molecular Weight: 212.294
• Mol file: 70898-14-5.mol

Synonyms:biphenyl-2,2'-diyldimethanamine

Chemical Property of BIPHENYL-2,2'-DIMETHANAMINE

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of BIPHENYL-2,2'-DIMETHANAMINE

There total 7 articles about BIPHENYL-2,2'-DIMETHANAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2,2'-bis(azidomethyl)biphenyl (1924-80-7) → biphenyl-2,2'-diyldimethanamine (70898-14-5)

Guidance literature:

2,2'-bis(azidomethyl)biphenyl; With triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 96h; Inert atmosphere;

With water; In tetrahydrofuran; for 2h; Reflux;

DOI:10.1016/j.bmcl.2011.11.017

Reference yield: 85.0%

2,2'-Bis-phthalimidomethyl-biphenyl (872823-56-8) → biphenyl-2,2'-diyldimethanamine (70898-14-5)

Guidance literature:

With hydrazine; In ethanol; at 50 ℃; for 5h;

DOI:10.1002/asia.201301123

Reference yield:

2,2'-bis-(bromomethyl)-1,1'-biphenyl (38274-14-5) → biphenyl-2,2'-diyldimethanamine (70898-14-5)

Guidance literature:

Multi-step reaction with 2 steps

1: NaN₃ / dimethylformamide

2: H₂ / Pd-C

With sodium azide; hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide;

DOI:10.1021/jo01332a037

upstream raw materials:

2,2'-Bis-phthalimidomethyl-biphenyl

2,2'-bis(azidomethyl)biphenyl

2,2'-bis-(bromomethyl)-1,1'-biphenyl

diphenic acid dimethyl ester