(3-Amino-1-benzothien-2-YL)(2-nitrophenyl)methanone

Base Information

Chemical Name:(3-Amino-1-benzothien-2-YL)(2-nitrophenyl)methanone
CAS No.:310462-61-4
Molecular Formula:C₁₅H₁₀N₂O₃S
Molecular Weight:298.322
Hs Code.:
European Community (EC) Number:668-443-8

Synonyms:(3-AMINO-1-BENZOTHIEN-2-YL)(2-NITROPHENYL)METHANONE;AKOS024321104

Suppliers and Price of (3-Amino-1-benzothien-2-YL)(2-nitrophenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (3-Amino-1-benzothien-2-YL)(2-nitrophenyl)methanone

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:298.04121336
Heavy Atom Count:21
Complexity:426

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=C(S2)C(=O)C3=CC=CC=C3[N+](=O)[O-])N

Technology Process of (3-Amino-1-benzothien-2-YL)(2-nitrophenyl)methanone

There total 1 articles about (3-Amino-1-benzothien-2-YL)(2-nitrophenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 34761-11-0
2-cyanothiophenol

: 6851-99-6
2-bromo-1-(2-nitrophenyl)ethanone

: 310462-61-4
3-amino-2-(2-nitrobenzoyl)benzothiophene

Guidance literature:: 2-cyanothiophenol; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

2-bromo-1-(2-nitrophenyl)ethanone; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1002/jhet.5570370430

Reference yield:

: 310462-61-4
3-amino-2-(2-nitrobenzoyl)benzothiophene

: 243-68-5
benzo[4,5]thieno[3,2-b]quinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / NaH / dimethylformamide / 2 h / 20 °C

2: 33 percent / POCl₃ / 3 h / Heating

3: 63 percent / HCl; H₂ / 10 percent Pd/C / methanol / 2 h / 760 Torr

With hydrogenchloride; hydrogen; sodium hydride; trichlorophosphate; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide; 1: Reduction / 2: Chlorination / 3: catalytic dehalogenation;
DOI:10.1002/jhet.5570370430