6-tert-butyl-2-(hydroxy-tert-butyl)-4-methylene-2,5-cyclohedanedienone

Base Information

• Chemical Name: 6-tert-butyl-2-(hydroxy-tert-butyl)-4-methylene-2,5-cyclohedanedienone
• CAS No.: 124755-19-7
• Molecular Formula: C15H22 O2
• Molecular Weight: 234.33
• Mol file: 124755-19-7.mol

Synonyms:6-tert-butyl-2-(hydroxy-tert-butyl)-4-methylene-2,5-cyclohedanedienone;QM-OH;6-TERT-BUTYL-2-(HYDROXY-TERT-BUTYL)-4-METHYLENE-2,5-CYCLOHEXADIENONE

Chemical Property of 6-tert-butyl-2-(hydroxy-tert-butyl)-4-methylene-2,5-cyclohedanedienone

Chemical Property:

• Vapor Pressure: 2.11E-06mmHg at 25°C
• Boiling Point: 353.3°Cat760mmHg
• PKA: 14.73±0.10(Predicted)
• Flash Point: 150.6°C
• PSA: 37.30000
• Density: 1g/cm³
• LogP: 3.04270

Purity/Quality:

95%+ or 98%+ ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-tert-butyl-2-(hydroxy-tert-butyl)-4-methylene-2,5-cyclohedanedienone

There total 1 articles about 6-tert-butyl-2-(hydroxy-tert-butyl)-4-methylene-2,5-cyclohedanedienone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-tert-butyl-2-(2'-hydroxy-1',1'-dimethylethyl)-4-methylphenol (112700-14-8) → 6-tert-butyl-2-(2'-hydroxy-1',1'-dimethylethyl)-4-methylene-2,5-cyclohexadienone (124755-19-7)

Guidance literature:

With silver(l) oxide; In acetonitrile; at 25 ℃; for 0.416667h;

DOI:10.1021/tx960115+

Reference yield:

deoxyribonucleic acid + 6-tert-butyl-2-(2'-hydroxy-1',1'-dimethylethyl)-4-methylene-2,5-cyclohexadienone (124755-19-7) → 2-amino-7-[3-tert-butyl-4-hydroxy-5-(2-hydroxy-1,1-dimethyl-ethyl)-benzyl]-1,7-dihydro-purin-6-one + (2R,3S,5R)-5-{6-[3-tert-Butyl-4-hydroxy-5-(2-hydroxy-1,1-dimethyl-ethyl)-benzylamino]-purin-9-yl}-2-hydroxymethyl-tetrahydro-furan-3-ol + 2-[3-tert-Butyl-4-hydroxy-5-(2-hydroxy-1,1-dimethyl-ethyl)-benzylamino]-9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one + 2-Amino-1-[3-tert-butyl-4-hydroxy-5-(2-hydroxy-1,1-dimethyl-ethyl)-benzyl]-9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one

Guidance literature:

deoxyribonucleic acid; 6-tert-butyl-2-(2'-hydroxy-1',1'-dimethylethyl)-4-methylene-2,5-cyclohexadienone; With DNase Ir; snake venom phosphodiesterase; In water; acetonitrile; at 30 - 37 ℃; for 5.5h;

In methanol; phosphate buffer; at 37 ℃; for 20h;

DOI:10.1021/tx960115+

Reference yield:

deoxyribonucleic acid + 6-tert-butyl-2-(2'-hydroxy-1',1'-dimethylethyl)-4-methylene-2,5-cyclohexadienone (124755-19-7) → (2R,3S,5R)-5-{6-[3-tert-Butyl-4-hydroxy-5-(2-hydroxy-1,1-dimethyl-ethyl)-benzylamino]-purin-9-yl}-2-hydroxymethyl-tetrahydro-furan-3-ol + 2-[3-tert-Butyl-4-hydroxy-5-(2-hydroxy-1,1-dimethyl-ethyl)-benzylamino]-9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one + C25H35N5O6 + 2-Amino-1-[3-tert-butyl-4-hydroxy-5-(2-hydroxy-1,1-dimethyl-ethyl)-benzyl]-9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one

Guidance literature:

With DNase Ir; snake venom phosphodiesterase; In water; acetonitrile; at 30 - 37 ℃; for 5.5h;

DOI:10.1021/tx960115+

upstream raw materials:

6-tert-butyl-2-(2'-hydroxy-1',1'-dimethylethyl)-4-methylphenol