3β,7β,14-Trihydroxy-5β-card-20(22)-enolide

Base Information

• Chemical Name: 3β,7β,14-Trihydroxy-5β-card-20(22)-enolide
• CAS No.: 1173-21-3
• Molecular Formula: C₂₃H₃₄O₅
• Molecular Weight: 390.52
• Mol file: 1173-21-3.mol

Synonyms:5b-Card-20(22)-enolide, 3b,7b,14-trihydroxy- (7CI,8CI); Digitoxigenin, 7b-hydroxy- (6CI); 7b-Hydroxydigitoxigenin

Chemical Property of 3β,7β,14-Trihydroxy-5β-card-20(22)-enolide

Chemical Property:

• Vapor Pressure: 2.4E-16mmHg at 25°C
• Boiling Point: 589.4°C at 760 mmHg
• Flash Point: 203°C
• PSA: 86.99000
• Density: 1.297g/cm³
• LogP: 2.57510

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3β,7β,14-Trihydroxy-5β-card-20(22)-enolide

There total 6 articles about 3β,7β,14-Trihydroxy-5β-card-20(22)-enolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7β-Hydroxydigitoxin (18810-27-0) → 7β-hydroxydigitoxigenin (1173-21-3)

Guidance literature:

With acid; PhB(OH)2/H₂SO₄/AgNO₃;

DOI:10.1016/0039-128X(81)90017-9

Reference yield:

→ 4-((3S,7S,10S,13R,14S,17R)-3,7,14-Trihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one (1173-21-3,13075-79-1,77844-47-4,107493-39-0,107596-69-0)

Guidance literature:

Digitoxigenin, mikrobielle Oxidation;

DOI:10.1021/ja01093a035

Reference yield:

→ 7β-Hydroxy-digitoxigenin (1173-21-3,13075-79-1,77844-47-4,107493-39-0,107596-69-0)

Guidance literature:

7β-Hydroxy-digitoxosid (III) (C41H64O14), saure Hydrolyse;

upstream raw materials:

7β-Hydroxydigitoxin