BUTTPARK 39\07-98

Base Information

• Chemical Name: BUTTPARK 39\07-98
• CAS No.: 5983-52-8
• Molecular Formula: C₁₇H₁₆N₂O
• Molecular Weight: 264.327
• Mol file: 5983-52-8.mol

Synonyms:1,2,3,10b-tetrahydropyrimido<2,1-a>isoindol-6(2H)-one

Chemical Property of BUTTPARK 39\07-98

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

1,2,3,4,6,10B-HEXAHYDRO-10B-PHENYLPYRIMIDO(2,1-A)ISOINDOL-6-ONE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of BUTTPARK 39\07-98

There total 2 articles about BUTTPARK 39\07-98 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

2-Benzoylbenzoic acid (85-52-9) + Trimethylenediamine (109-76-2,54018-94-9) → 1,2,3,10b-tetrahydropyrimido<2,1-a>isoindol-6(2H)-one (5983-52-8)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; Heating;

DOI:10.1021/jm00069a011

Reference yield:

→ 1,2,3,10b-tetrahydropyrimido<2,1-a>isoindol-6(2H)-one (5983-52-8)

Guidance literature:

o-Bz-C6H4-CO2H, NH2-(CH2)3-NH2;

upstream raw materials:

2-Benzoylbenzoic acid

Trimethylenediamine

Refernces

• 1、 Mertens, Alfred,Zilch, Harald,Koenig, Bernhard,Schaefer, Wolfgang,Poll, Thomas,et al.. "Selective Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. New 2,3-Dihydrothiazoloisoindol-5(9bH)-ones and Related Compounds with Anti-HIV-1 Activity". . p. 2526 - 2535. Retrieved 2007/10/02.