Technology Process of Phe-Phe-Pro-Leu-Met-NH2*HCl
There total 13 articles about Phe-Phe-Pro-Leu-Met-NH2*HCl which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
acetic acid;
for 0.5h;
Ambient temperature;
DOI:10.1021/jm00157a029
- Guidance literature:
-
Multi-step reaction with 4 steps
1: N-methylmorpholine, hexamethylphosphoric acid triamide / dimethylformamide / 2 h / -20 °C
2: 89 percent / 1 N HCl / acetic acid / 0.5 h / Ambient temperature
3: N-methylmorpholine / dimethylformamide / 2 h / -20 °C
4: 95 percent / 1 N HCl / acetic acid / 0.5 h / Ambient temperature
With
4-methyl-morpholine; hydrogenchloride; N,N,N,N,N,N-hexamethylphosphoric triamide;
In
acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00157a029
- Guidance literature:
-
Multi-step reaction with 7 steps
1: N-methylmorpholine / dimethylformamide / 0.03 h / -20 °C
2: N-methylmorpholine / dimethylformamide / 2 h / -20 °C
3: 95 percent / 1 N HCl / acetic acid / 0.5 h / Ambient temperature
4: N-methylmorpholine, hexamethylphosphoric acid triamide / dimethylformamide / 2 h / -20 °C
5: 89 percent / 1 N HCl / acetic acid / 0.5 h / Ambient temperature
6: N-methylmorpholine / dimethylformamide / 2 h / -20 °C
7: 95 percent / 1 N HCl / acetic acid / 0.5 h / Ambient temperature
With
4-methyl-morpholine; hydrogenchloride; N,N,N,N,N,N-hexamethylphosphoric triamide;
In
acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00157a029
