Technology Process of Benzyl-((E)-(S)-1-benzyl-penta-2,4-dienyl)-carbamic acid methyl ester
There total 1 articles about Benzyl-((E)-(S)-1-benzyl-penta-2,4-dienyl)-carbamic acid methyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
ammonium cerium(IV) nitrate; potassium carbonate;
Yield given. Multistep reaction;
1.) CH2Cl2, RT, 3 h, 2.) CH3CN, -40 deg C, 1 h;
DOI:10.1248/cpb.44.948
- Guidance literature:
-
With
iodine; potassium iodide;
In
dichloromethane;
for 12h;
Ambient temperature;
DOI:10.1248/cpb.44.948
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 84 percent / I2, KI / CH2Cl2 / 12 h / Ambient temperature
2: 91 percent / AcOH / dimethylformamide / 1.5 h / Ambient temperature
3: 73 percent / aq. NaOH / methanol / 1 h / Ambient temperature
4: 94 percent / Li, NH3 (liq.) / tetrahydrofuran / 0.17 h / -78 °C
5: 84 percent / Jones reagent / acetone / 0.25 h / Ambient temperature
6: 74 percent / Et3N, 4-dimethylaminopyridine / tetrahydrofuran / 12 h / 60 °C
7: 78 percent / CsCO3 / methanol / 24 h / Ambient temperature
With
dmap; sodium hydroxide; jones reagent; ammonia; iodine; lithium; acetic acid; triethylamine; potassium iodide;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1248/cpb.44.948
