1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3-C-methyl-β-D-ribofuranose

Base Information

• Chemical Name: 1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3-C-methyl-β-D-ribofuranose
• CAS No.: 59896-10-5
• Molecular Formula: C₁₇H₂₀O₇
• Molecular Weight: 336.342
• Mol file: 59896-10-5.mol

Synonyms:1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3-C-methyl-β-D-ribofuranose

Chemical Property of 1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3-C-methyl-β-D-ribofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3-C-methyl-β-D-ribofuranose

There total 2 articles about 1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3-C-methyl-β-D-ribofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic anhydride (108-24-7) + Benzoic acid (2S,3S,4R)-4,5-dihydroxy-3-methyl-tetrahydro-furan-2-ylmethyl ester → 1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3-C-methyl-α-D-ribofuranose + 1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3-C-methyl-β-D-ribofuranose (59896-10-5)

Guidance literature:

With pyridine; dmap; at 20 ℃; for 0.5h;

DOI:10.1016/j.tet.2007.08.092

Reference yield:

→ 1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3-C-methyl-β-D-ribofuranose (59896-10-5)

Guidance literature:

Isopropyliden-Deriv. 12, Eg./Ac2O;

DOI:10.1021/jm00233a001

Reference yield: 82.0%

1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3-C-methyl-β-D-ribofuranose (59896-10-5) + 5-iodouracil (696-07-1) → 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-3-C-methyl-β-D-ribofuranosyl)-5-iodouracil

Guidance literature:

5-iodouracil; With 1,1,1,3,3,3-hexamethyl-disilazane; saccharin; In acetonitrile; for 0.5h; Reflux; Inert atmosphere;

1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3-C-methyl-β-D-ribofuranose; With trimethylsilyl trifluoromethanesulfonate; In acetonitrile; at 0 - 20 ℃; for 1h; Inert atmosphere;

DOI:10.2174/1573406415666190225112950

upstream raw materials:

acetic anhydride