1-(2-{2-[2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-5-formylamino-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-acryloyl)-pyrrolidine-2-carboxylic acid

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Chemical Name:1-(2-{2-[2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-5-formylamino-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-acryloyl)-pyrrolidine-2-carboxylic acid
CAS No.:121778-96-9
Molecular Formula:C₃₆H₅₄N₆O₉
Molecular Weight:714.86
Hs Code.:

1-(2-{2-[2-(2-<i>tert</i>-butoxycarbonylamino-3-methyl-butyrylamino)-5-formylamino-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-acryloyl)-pyrrolidine-2-carboxylic acid

Synonyms:1-(2-{2-[2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-5-formylamino-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-acryloyl)-pyrrolidine-2-carboxylic acid

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Chemical Property of 1-(2-{2-[2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-5-formylamino-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-acryloyl)-pyrrolidine-2-carboxylic acid

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Technology Process of 1-(2-{2-[2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-5-formylamino-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-acryloyl)-pyrrolidine-2-carboxylic acid

There total 1 articles about 1-(2-{2-[2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-5-formylamino-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-acryloyl)-pyrrolidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 923014-91-9
1-(2-{2-[2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-5-formylamino-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-acryloyl)-pyrrolidine-2-carboxylic acid 2,2,2-trichloro-ethyl ester

: 121778-96-9
1-(2-{2-[2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-5-formylamino-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-acryloyl)-pyrrolidine-2-carboxylic acid

Guidance literature:: With acetic acid; zinc; at 20 ℃; for 5h;
DOI:10.1021/jm061051v

Reference yield: 77.0%

: 121778-96-9
1-(2-{2-[2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-5-formylamino-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-acryloyl)-pyrrolidine-2-carboxylic acid

: 1-(2-{2-[2-(2-amino-3-methyl-butyrylamino)-5-formylamino-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-acryloyl)-pyrrolidine-2-carboxylic acid 2,2,2-trichloro-ethyl ester; compound with trifluoro-acetic acid

: C₆₉H₉₉Cl₃N₁₂O₁₅

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In chloroform; at 0 - 20 ℃; for 22h;
DOI:10.1021/jm061051v

Reference yield: 76.0%

: 121778-96-9
1-(2-{2-[2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-5-formylamino-pentanoylamino]-4-methyl-pentanoylamino}-3-phenyl-acryloyl)-pyrrolidine-2-carboxylic acid

: 1-(2-{2-[2-(2-amino-3-methyl-butyrylamino)-5-formylamino-pentanoylamino]-4-methyl-pentanoylamino}-3-pyridin-3-yl-acryloyl)-pyrrolidine-2-carboxylic acid methyl ester; compound with trifluoro-acetic acid

: C₆₇H₉₉N₁₃O₁₅

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In chloroform; at 0 - 20 ℃; for 21h;
DOI:10.1021/jm061051v