2,6-bis[4-(N-hydroxyamidino)phenyl]-7,8-dimethylimidazo[1,2-a]pyridine

Base Information

• Chemical Name: 2,6-bis[4-(N-hydroxyamidino)phenyl]-7,8-dimethylimidazo[1,2-a]pyridine
• CAS No.: 1016558-33-0
• Molecular Formula: C₂₃H₂₂N₆O₂
• Molecular Weight: 414.467
• Mol file: 1016558-33-0.mol

Synonyms:2,6-bis[4-(N-hydroxyamidino)phenyl]-7,8-dimethylimidazo[1,2-a]pyridine

Chemical Property of 2,6-bis[4-(N-hydroxyamidino)phenyl]-7,8-dimethylimidazo[1,2-a]pyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 2,6-bis[4-(N-hydroxyamidino)phenyl]-7,8-dimethylimidazo[1,2-a]pyridine

There total 1 articles about 2,6-bis[4-(N-hydroxyamidino)phenyl]-7,8-dimethylimidazo[1,2-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2,6-bis(4-cyanophenyl)-7,8-dimethylimidazo[1,2-a]pyridine (1016558-30-7) → 2,6-bis[4-(N-hydroxyamidino)phenyl]-7,8-dimethylimidazo[1,2-a]pyridine (1016558-33-0)

Guidance literature:

With hydroxylamine hydrochloride; potassium tert-butylate; In dimethyl sulfoxide; at 20 ℃;

DOI:10.1016/j.bmc.2007.10.042

Reference yield: 59.0%

2,6-bis[4-(N-hydroxyamidino)phenyl]-7,8-dimethylimidazo[1,2-a]pyridine (1016558-33-0) + dimethyl sulfate (77-78-1) → 2,6-bis[4-(N-methoxyamidino)phenyl]-7,8-dimethylimidazo[1,2-a]pyridine (1016558-36-3)

Guidance literature:

With lithium hydroxide; In water; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2007.10.042

Reference yield:

2,6-bis[4-(N-hydroxyamidino)phenyl]-7,8-dimethylimidazo[1,2-a]pyridine (1016558-33-0) + acetic anhydride (108-24-7) → 2,6-bis(4-amidinophenyl)-7,8-dimethylimidazo[1,2-a]pyridine acetic acid salt

Guidance literature:

2,6-bis[4-(N-hydroxyamidino)phenyl]-7,8-dimethylimidazo[1,2-a]pyridine; acetic anhydride; With acetic acid;

With hydrogen; palladium on activated charcoal; In ethanol; ethyl acetate; at 20 ℃; for 4h; under 2585.81 Torr; Further stages.;

DOI:10.1016/j.bmc.2007.10.042

upstream raw materials:

2,6-bis(4-cyanophenyl)-7,8-dimethylimidazo[1,2-a]pyridine

Downstream raw materials:

2,6-bis[4-(N-methoxyamidino)phenyl]-7,8-dimethylimidazo[1,2-a]pyridine