Hydrocortisone 21-propionate

Base Information

Chemical Name:Hydrocortisone 21-propionate
CAS No.:6677-98-1
Molecular Formula:C24H34O6
Molecular Weight:418.53
Hs Code.:
DSSTox Substance ID:DTXSID70872918
Nikkaji Number:J407.515C
Wikidata:Q81978554
ChEMBL ID:CHEMBL254195
Mol file:6677-98-1.mol

Synonyms:hydrocortisone 21-propionate;6677-98-1;[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate;Cortisol, 21-propionate;SCHEMBL180225;CHEMBL254195;DTXSID70872918;11,17-Dihydroxy-21-(1-oxopropoxy)pregn-4-ene-3,20-dione (11beta)-;AKOS015969743;Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-(1-oxopropoxy)-, (11beta)-

Suppliers and Price of Hydrocortisone 21-propionate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Hydrocortisone21-Propionate
10mg
$ 140.00

Total 5 raw suppliers

Chemical Property of Hydrocortisone 21-propionate

Chemical Property:

Vapor Pressure:3.73E-16mmHg at 25°C
Refractive Index:1.5200 (estimate)
Boiling Point:585.6°C at 760 mmHg
Flash Point:196.9°C
PSA：100.90000
Density:1.24g/cm³
LogP:2.74250
Water Solubility.:11.6mg/L(25 oC)
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:418.23553880
Heavy Atom Count:30
Complexity:802

Purity/Quality:

99% ^*data from raw suppliers

Hydrocortisone21-Propionate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)OCC(=O)C1(CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C)O
Isomeric SMILES:CCC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)O
Uses Hydrocortisone 21-Propionate is a metabolite of Hydrocortisone 17-Butyrate 21-Propionate (H714665); a synthetic adrenocorticosteroid that acts as an anti-inflammatory and anti-pruritic agent. It is used as a topical for the treatment of dermatologic disorders such as atopic dermatitis and psoriasis.

Technology Process of Hydrocortisone 21-propionate

There total 1 articles about Hydrocortisone 21-propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: