Dimethyl-thiocarbamic acid S-(4-chlorocarbonyl-phenyl) ester

Base Information

• Chemical Name: Dimethyl-thiocarbamic acid S-(4-chlorocarbonyl-phenyl) ester
• CAS No.: 1026905-93-0
• Molecular Formula: C₁₀H₁₀ClNO₂S
• Molecular Weight: 243.714
• Mol file: 1026905-93-0.mol

Synonyms:Dimethyl-thiocarbamic acid S-(4-chlorocarbonyl-phenyl) ester

Chemical Property of Dimethyl-thiocarbamic acid S-(4-chlorocarbonyl-phenyl) ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of Dimethyl-thiocarbamic acid S-(4-chlorocarbonyl-phenyl) ester

There total 2 articles about Dimethyl-thiocarbamic acid S-(4-chlorocarbonyl-phenyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-<(dimethylcarbamoyl)thio>benzoic acid (13511-91-6) → Dimethyl-thiocarbamic acid S-(4-chlorocarbonyl-phenyl) ester (1026905-93-0)

Guidance literature:

With (COCl₂)2; N,N-dimethyl-formamide; In dichloromethane; for 3h; Ambient temperature;

DOI:10.1021/jo961527q

Reference yield:

S-(4-carbomethoxyphenyl) N,N-dimethylthiocarbamate (13511-93-8) → Dimethyl-thiocarbamic acid S-(4-chlorocarbonyl-phenyl) ester (1026905-93-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / Me₃SiI / 2 h / 100 °C

2: (COCl₂)2, DMF / CH₂Cl₂ / 3 h / Ambient temperature

With trimethylsilyl iodide; (COCl₂)2; N,N-dimethyl-formamide; In dichloromethane;

DOI:10.1021/jo961527q

Reference yield: 96.0%

Dimethyl-thiocarbamic acid S-(4-chlorocarbonyl-phenyl) ester (1026905-93-0) + [4,4-Bis-(4-benzyloxy-phenyl)-pentyl]-methyl-amine (184866-19-1) → Dimethyl-thiocarbamic acid S-(4-{[4,4-bis-(4-benzyloxy-phenyl)-pentyl]-methyl-carbamoyl}-phenyl) ester (184866-22-6)

Guidance literature:

With triethylamine; In dichloromethane; Ambient temperature;

DOI:10.1021/jo961527q

upstream raw materials:

4-<(dimethylcarbamoyl)thio>benzoic acid

S-(4-carbomethoxyphenyl) N,N-dimethylthiocarbamate

Downstream raw materials:

Dimethyl-thiocarbamic acid S-(4-{[4,4-bis-(4-benzyloxy-phenyl)-pentyl]-methyl-carbamoyl}-phenyl) ester

N-[4,4-Bis-(4-benzyloxy-phenyl)-pentyl]-4-mercapto-N-methyl-benzamide