(1R,2R,3R,4S,5R,6S)-tert-butyl 2-benzyl-1-hydroxy-3,5-bis(4-methoxyphenyl)-4,6-dinitrocyclohexanecarboxylate

Base Information

Chemical Name:(1R,2R,3R,4S,5R,6S)-tert-butyl 2-benzyl-1-hydroxy-3,5-bis(4-methoxyphenyl)-4,6-dinitrocyclohexanecarboxylate
CAS No.:1361018-72-5
Molecular Formula:C₃₂H₃₆N₂O₉
Molecular Weight:592.646
Hs Code.:

Synonyms:(1R,2R,3R,4S,5R,6S)-tert-butyl 2-benzyl-1-hydroxy-3,5-bis(4-methoxyphenyl)-4,6-dinitrocyclohexanecarboxylate

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Chemical Property of (1R,2R,3R,4S,5R,6S)-tert-butyl 2-benzyl-1-hydroxy-3,5-bis(4-methoxyphenyl)-4,6-dinitrocyclohexanecarboxylate

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Technology Process of (1R,2R,3R,4S,5R,6S)-tert-butyl 2-benzyl-1-hydroxy-3,5-bis(4-methoxyphenyl)-4,6-dinitrocyclohexanecarboxylate

There total 1 articles about (1R,2R,3R,4S,5R,6S)-tert-butyl 2-benzyl-1-hydroxy-3,5-bis(4-methoxyphenyl)-4,6-dinitrocyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 3179-10-0
1-methoxy-4-(2-nitro-vinyl)-benzene

: t-butyl 2-oxo-4-phenylbutanoate

: 1361018-72-5
(1R,2R,3R,4S,5R,6S)-tert-butyl 2-benzyl-1-hydroxy-3,5-bis(4-methoxyphenyl)-4,6-dinitrocyclohexanecarboxylate

Guidance literature:: t-butyl 2-oxo-4-phenylbutanoate; With C₄₂H₅₇N₅O₃S; In tetrahydrofuran; at 0 ℃; for 0.5h; Molecular sieve; Inert atmosphere;

1-methoxy-4-(2-nitro-vinyl)-benzene; In tetrahydrofuran; at 0 ℃; for 72h; enantioselective reaction; Inert atmosphere; Molecular sieve;
DOI:10.1055/s-0036-1588940