(R)-3-amino-2,3,4-trideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-2-<1-(phenylmethoxy)ethyl>-D-erythro-pentonic acid, β lactam

Base Information

Chemical Name:(R)-3-amino-2,3,4-trideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-2-<1-(phenylmethoxy)ethyl>-D-erythro-pentonic acid, β lactam
CAS No.:91994-33-1
Molecular Formula:C₃₀H₃₇NO₃Si
Molecular Weight:487.714
Hs Code.:

Synonyms:(R)-3-amino-2,3,4-trideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-2-<1-(phenylmethoxy)ethyl>-D-erythro-pentonic acid, β lactam

Suppliers and Price of (R)-3-amino-2,3,4-trideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-2-<1-(phenylmethoxy)ethyl>-D-erythro-pentonic acid, β lactam

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-3-amino-2,3,4-trideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-2-<1-(phenylmethoxy)ethyl>-D-erythro-pentonic acid, β lactam

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-3-amino-2,3,4-trideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-2-<1-(phenylmethoxy)ethyl>-D-erythro-pentonic acid, β lactam

There total 7 articles about (R)-3-amino-2,3,4-trideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-2-<1-(phenylmethoxy)ethyl>-D-erythro-pentonic acid, β lactam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 91994-26-2
(4R,5S)-4-((S)-1-Benzyloxy-ethyl)-5-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-cyclopent-2-enone

: 91994-33-1
(R)-3-amino-2,3,4-trideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-2-<1-(phenylmethoxy)ethyl>-D-erythro-pentonic acid, β lactam

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) H₂NOH*HCl, NaOAc; 2.) TsCl / 2.) dimethylaminopropylamine / 1.) EtOH, 42 h; 2.) pyridine, r.t. -> 65 deg C

3: 381 mg / potassium permanganate, sodium periodate, sodium bicarbonate / 2-methyl-propan-2-ol; H₂O / 1.5 h / Ambient temperature

4: 240 mg / 2 M sodium methoxide / methanol / 1.5 h / 0 °C

5: 2.) triethylamine; 3.) dicyclohexylcarbodiimide / 1.) trifluoroacetic acid, 0 deg C, 20 min; 2.) acetonitrile, 5 min; 3.) 65 deg C, 5 h

With potassium permanganate; sodium periodate; hydroxylamine hydrochloride; sodium methylate; sodium acetate; sodium hydrogencarbonate; triethylamine; p-toluenesulfonyl chloride; dicyclohexyl-carbodiimide; 1-amino-3-(dimethylamino)propane; In methanol; water; tert-butyl alcohol;
DOI:10.1021/ja00333a053

Reference yield:

: 91994-27-3
<5S-<5α(S^*),6β>>-6-<2-<<(1,1-dimethylethyl)diphenylsilyl>oxy>ethyl>-5-<1-(phenylmethoxy)ethyl>-2-piperidinone

: 91994-33-1
(R)-3-amino-2,3,4-trideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-2-<1-(phenylmethoxy)ethyl>-D-erythro-pentonic acid, β lactam

Guidance literature:: Multi-step reaction with 4 steps

2: 381 mg / potassium permanganate, sodium periodate, sodium bicarbonate / 2-methyl-propan-2-ol; H₂O / 1.5 h / Ambient temperature

3: 240 mg / 2 M sodium methoxide / methanol / 1.5 h / 0 °C

4: 2.) triethylamine; 3.) dicyclohexylcarbodiimide / 1.) trifluoroacetic acid, 0 deg C, 20 min; 2.) acetonitrile, 5 min; 3.) 65 deg C, 5 h

With potassium permanganate; sodium periodate; sodium methylate; sodium hydrogencarbonate; triethylamine; dicyclohexyl-carbodiimide; In methanol; water; tert-butyl alcohol;
DOI:10.1021/ja00333a053

Reference yield:

: 91994-28-4
1,1-dimethylethyl <2R-<2a,3β(R^*)>>-2-<2-<<(1,1-dimethylethyl)diphenylsilyl>oxy>ethyl>-6-oxo-3-<1-(phenylmethoxy)ethyl>-1-piperidinecarboxylate

: 91994-33-1
(R)-3-amino-2,3,4-trideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-2-<1-(phenylmethoxy)ethyl>-D-erythro-pentonic acid, β lactam

Guidance literature:: Multi-step reaction with 4 steps

2: 381 mg / potassium permanganate, sodium periodate, sodium bicarbonate / 2-methyl-propan-2-ol; H₂O / 1.5 h / Ambient temperature

3: 240 mg / 2 M sodium methoxide / methanol / 1.5 h / 0 °C

4: 2.) triethylamine; 3.) dicyclohexylcarbodiimide / 1.) trifluoroacetic acid, 0 deg C, 20 min; 2.) acetonitrile, 5 min; 3.) 65 deg C, 5 h

With potassium permanganate; sodium periodate; sodium methylate; sodium hydrogencarbonate; triethylamine; dicyclohexyl-carbodiimide; In methanol; water; tert-butyl alcohol;
DOI:10.1021/ja00333a053