(S)-2-((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-propionic acid pentafluorophenyl ester

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Chemical Name:(S)-2-((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-propionic acid pentafluorophenyl ester
CAS No.:117169-87-6
Molecular Formula:C₂₈H₃₂F₅N₃O₇
Molecular Weight:617.57
Hs Code.:

Synonyms:(S)-2-((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-propionic acid pentafluorophenyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-2-((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-propionic acid pentafluorophenyl ester

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Technology Process of (S)-2-((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-propionic acid pentafluorophenyl ester

There total 2 articles about (S)-2-((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-propionic acid pentafluorophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 771-61-9
2,3,4,5,6-pentafluorophenol

: 31310-97-1
N^α-tert-butyloxycarbonyl-N^ε-benzyloxycarbonyllysyl-alanine

: 117169-87-6
(S)-2-((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-propionic acid pentafluorophenyl ester

Guidance literature:: With dicyclohexyl-carbodiimide; In 1,4-dioxane; N,N-dimethyl-formamide; at 20 ℃; for 1h;

Reference yield:

: 22839-06-1
Boc-Lys(Z)-Ala-OMe

: 117169-87-6
(S)-2-((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-propionic acid pentafluorophenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 66 percent / NaOH / aq. propan-2-ol / 2 h / 20 °C

2: 84 percent / DCC / dimethylformamide; dioxane / 1 h / 20 °C

With sodium hydroxide; dicyclohexyl-carbodiimide; In 1,4-dioxane; N,N-dimethyl-formamide; isopropyl alcohol;