N-(2-chloroallyl)-N-(4-chlorophenyl)-2,2,2-trifluoroacetamide

Base Information

• Chemical Name: N-(2-chloroallyl)-N-(4-chlorophenyl)-2,2,2-trifluoroacetamide
• CAS No.: 1221170-76-8
• Molecular Formula: C₁₁H₈Cl₂F₃NO
• Molecular Weight: 298.092
• Mol file: 1221170-76-8.mol

Synonyms:N-(2-chloroallyl)-N-(4-chlorophenyl)-2,2,2-trifluoroacetamide

Chemical Property of N-(2-chloroallyl)-N-(4-chlorophenyl)-2,2,2-trifluoroacetamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-(2-chloroallyl)-N-(4-chlorophenyl)-2,2,2-trifluoroacetamide

There total 1 articles about N-(2-chloroallyl)-N-(4-chlorophenyl)-2,2,2-trifluoroacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-(2-chloroallyl)-4-chloroaniline (57662-86-9) + trifluoroacetic anhydride (407-25-0) → N-(2-chloroallyl)-N-(4-chlorophenyl)-2,2,2-trifluoroacetamide (1221170-76-8)

Guidance literature:

With copper(II) bis(trifluoromethanesulfonate); In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1002/adsc.200900565

Reference yield: 100.0%

N-(2-chloroallyl)-N-(4-chlorophenyl)-2,2,2-trifluoroacetamide (1221170-76-8) → N-(3-chloro-2-oxopropyl)-N-(4-chlorophenyl)-2,2,2-trifluoroacetamide (1221170-58-6)

Guidance literature:

With calcium hypochlorite; acetic acid; In water; acetone; at 0 ℃; for 1h; chemoselective reaction;

DOI:10.1002/adsc.200900565

upstream raw materials:

N-(2-chloroallyl)-4-chloroaniline

trifluoroacetic anhydride

Downstream raw materials:

N-(3-chloro-2-oxopropyl)-N-(4-chlorophenyl)-2,2,2-trifluoroacetamide