Cinitapride

Base Information

• Chemical Name: Cinitapride
• CAS No.: 66564-14-5
• Molecular Formula: C21H30 N4 O4
• Molecular Weight: 552.57
• UNII: R8I97I2L24
• DSSTox Substance ID: DTXSID60867232
• Nikkaji Number: J18.746A
• Wikipedia: Cinitapride
• Wikidata: Q5121012
• NCI Thesaurus Code: C77257
• Metabolomics Workbench ID: 43725
• ChEMBL ID: CHEMBL2104523
• Mol file: 66564-14-5.mol

Synonyms:4-Amino-N-(1-(3-cyclohexen-1-ylmethyl)-4-piperidyl)-2-ethoxy-5-nitrobenzamide;Blaston;Cidine;cinitapride;cinitapride tartrate

Chemical Property of Cinitapride

Chemical Property:

• Vapor Pressure: 1.94E-13mmHg at 25°C
• Refractive Index: 1.602
• Boiling Point: 579.8°C at 760 mmHg
• PKA: 12.62±0.20(Predicted)
• Flash Point: 304.5°C
• PSA: 113.41000
• Density: 1.24
• LogP: 4.55940
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 402.22670545
• Heavy Atom Count: 29
• Complexity: 586

Purity/Quality:

98%,99%, ^*data from raw suppliers

Cinitapride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=CC(=C(C=C1C(=O)NC2CCN(CC2)CC3CCC=CC3)[N+](=O)[O-])N
• Recent ClinicalTrials: Efficacy and Safety of Cinitapride Tablets in the Treatment of Mild to Moderate Functional Dyspepsia
• Description: Cinitapride is a substituted benzamide dopamine receptor antagonist effective in the treatment of gastroesophageal reflux and a variety of gastrointestinal motility disorders. It generates strong procholinergic activity in the gastrointestinal tract by elevating the serotonergic transmission in the mysenteric plexus.
• Uses: A novel prokinetic benzamide-stimulating gastrointestinal motility agent and antiucer agent. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors (1,2,3). A novel prokinetic benzamide-stimulating gastrointestinal motility agent and antiucer agent. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors. serotonin-norepinephrine reuptake inhibitor, antidepressant