ethyl 1?(4?chlorophenyl)?4?((4?chlorophenyl)amino)?2?methyl?5?oxo?2,5?dihydro?1H?pyrrole?2?carboxylate

Base Information

• Chemical Name: ethyl 1?(4?chlorophenyl)?4?((4?chlorophenyl)amino)?2?methyl?5?oxo?2,5?dihydro?1H?pyrrole?2?carboxylate
• CAS No.: 223392-77-6
• Molecular Formula: C₂₀H₁₈Cl₂N₂O₃
• Molecular Weight: 405.281

Synonyms:ethyl 1?(4?chlorophenyl)?4?((4?chlorophenyl)amino)?2?methyl?5?oxo?2,5?dihydro?1H?pyrrole?2?carboxylate

Chemical Property of ethyl 1?(4?chlorophenyl)?4?((4?chlorophenyl)amino)?2?methyl?5?oxo?2,5?dihydro?1H?pyrrole?2?carboxylate

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

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Technology Process of ethyl 1?(4?chlorophenyl)?4?((4?chlorophenyl)amino)?2?methyl?5?oxo?2,5?dihydro?1H?pyrrole?2?carboxylate

There total 2 articles about ethyl 1?(4?chlorophenyl)?4?((4?chlorophenyl)amino)?2?methyl?5?oxo?2,5?dihydro?1H?pyrrole?2?carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-oxo-propionic acid ethyl ester (617-35-6) + 4-chloro-aniline (106-47-8) → ethyl 1?(4?chlorophenyl)?4?((4?chlorophenyl)amino)?2?methyl?5?oxo?2,5?dihydro?1H?pyrrole?2?carboxylate (223392-77-6)

Guidance literature:

With CoFe₂O₄ nanoparticles base catalyst; In ethanol; water; for 0.166667h; Microwave irradiation; Green chemistry;

DOI:10.1002/aoc.3536

Reference yield: 66.0%

→ ethyl 1?(4?chlorophenyl)?4?((4?chlorophenyl)amino)?2?methyl?5?oxo?2,5?dihydro?1H?pyrrole?2?carboxylate (223392-77-6)

Guidance literature:

With bis(cyclopentadienyl)titanium dichloride; 4-nitro-benzoic acid; In water; chlorobenzene; at 50 ℃; for 6h;

Reference yield: 80.0%

ethyl 1?(4?chlorophenyl)?4?((4?chlorophenyl)amino)?2?methyl?5?oxo?2,5?dihydro?1H?pyrrole?2?carboxylate (223392-77-6) → 1-(4-chloro-phenyl)-2-methyl-4,5-dioxo-pyrrolidine-2-carboxylic acid ethyl ester (223392-85-6)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

2-oxo-propionic acid ethyl ester

4-chloro-aniline

Downstream raw materials:

1-(4-chloro-phenyl)-2-methyl-4,5-dioxo-pyrrolidine-2-carboxylic acid ethyl ester

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