1-tert-butoxycarbonyl-4S-(3,5-bistrifluoromethylbenzyloxy)-3R-2-tolylpiperidine

Base Information

Chemical Name:1-tert-butoxycarbonyl-4S-(3,5-bistrifluoromethylbenzyloxy)-3R-2-tolylpiperidine
CAS No.:869720-16-1
Molecular Formula:C₂₆H₂₉F₆NO₃
Molecular Weight:517.512
Hs Code.:

Synonyms:1-tert-butoxycarbonyl-4S-(3,5-bistrifluoromethylbenzyloxy)-3R-2-tolylpiperidine

Suppliers and Price of 1-tert-butoxycarbonyl-4S-(3,5-bistrifluoromethylbenzyloxy)-3R-2-tolylpiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-tert-butoxycarbonyl-4S-(3,5-bistrifluoromethylbenzyloxy)-3R-2-tolylpiperidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-tert-butoxycarbonyl-4S-(3,5-bistrifluoromethylbenzyloxy)-3R-2-tolylpiperidine

There total 1 articles about 1-tert-butoxycarbonyl-4S-(3,5-bistrifluoromethylbenzyloxy)-3R-2-tolylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 869720-08-1
1-tert-butoxycarbonyl-3R-(2-methylphenyl)-4S-hydroxypiperidine

: 32247-96-4
3,5-bis(trifluoromethyl)benzyl bromide

: 869720-16-1
1-tert-butoxycarbonyl-4S-(3,5-bistrifluoromethylbenzyloxy)-3R-2-tolylpiperidine

Guidance literature:: 1-tert-butoxycarbonyl-3R-(2-methylphenyl)-4S-hydroxypiperidine; With sodium t-butanolate; In tetrahydrofuran; for 0.25h;

3,5-bis(trifluoromethyl)benzyl bromide; In tetrahydrofuran; for 3h; Heating / reflux;

Reference yield:

: 869720-16-1
1-tert-butoxycarbonyl-4S-(3,5-bistrifluoromethylbenzyloxy)-3R-2-tolylpiperidine

: 869720-24-1
4S-(3,5-bistrifluoromethylbenzyloxy)-3R-2-tolylpiperidine

Guidance literature:: 1-tert-butoxycarbonyl-4S-(3,5-bistrifluoromethylbenzyloxy)-3R-2-tolylpiperidine; With trifluoroacetic acid; In dichloromethane;

With sodium hydrogencarbonate; In dichloromethane; water;