(2S,3R)-2,3-Dibenzyloxyhexanal

Base Information

• Chemical Name: (2S,3R)-2,3-Dibenzyloxyhexanal
• CAS No.: 131087-29-1
• Molecular Formula: C₂₀H₂₄O₃
• Molecular Weight: 312.409
• Mol file: 131087-29-1.mol

Synonyms:(2S,3R)-2,3-Dibenzyloxyhexanal

Chemical Property of (2S,3R)-2,3-Dibenzyloxyhexanal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3R)-2,3-Dibenzyloxyhexanal

There total 9 articles about (2S,3R)-2,3-Dibenzyloxyhexanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

(2S,3S,4R)-3,4-Dibenzyloxy-1,2-dihydroxyheptane (131087-28-0,145679-70-5,146143-42-2) → (2S,3R)-2,3-Dibenzyloxyhexanal (131087-29-1)

Guidance literature:

With lead(IV) acetate; In benzene; for 0.333333h; Ambient temperature;

Reference yield:

(2R,3S)-2,3-bis(benzyloxy)hexan-1-ol (887502-26-3) → (2S,3R)-2,3-Dibenzyloxyhexanal (131087-29-1)

Guidance literature:

With sodium acetate; pyridinium chlorochromate; In dichloromethane; at 0 ℃;

DOI:10.1002/chem.200501127

Reference yield:

C11H22O4 → (2S,3R)-2,3-Dibenzyloxyhexanal (131087-29-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: NaH / various solvent(s); tetrahydrofuran / 0 °C

1.2: n-Bu₄NI / various solvent(s); tetrahydrofuran / 20 °C

2.1: 1.85 g / aq. HCl / methanol / 0 °C

3.1: pyridinium chlorochromate; NaOAc / CH₂Cl₂ / 0 °C

With hydrogenchloride; sodium acetate; sodium hydride; pyridinium chlorochromate; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1002/chem.200501127

upstream raw materials:

(2S,3S,4R)-3,4-Dibenzyloxy-1,2-dihydroxyheptane

(2R,3S)-2,3-bis(benzyloxy)hexan-1-ol

(E)-2-Hexen-1-ol

2-[((E)-Hex-2-enyl)oxy]-tetrahydro-pyran

Downstream raw materials:

6-((1S,2R)-1,2-Bis-benzyloxy-pentyl)-4-hydroxy-5,6-dihydro-pyran-2-one

(6RS,1'S,2'R)-6-(1',2'-Dibenzyloxypentyl)-5,6-dihydro-4-methoxypyrane-2-one

(6R,1'S,2'R)-6-(1',2'-Dihydroxypentyl)-5,6-dihydro-4-methoxypyrane-2-one

hydroxypestalotin