(S)-N,N-dimethyl-1-[2-(diphenylphosphanyl)-3-methoxyphenyl]ethylamine

Base Information

• Chemical Name: (S)-N,N-dimethyl-1-[2-(diphenylphosphanyl)-3-methoxyphenyl]ethylamine
• CAS No.: 1053241-01-2
• Molecular Formula: C₂₃H₂₆NOP
• Molecular Weight: 363.439
• Mol file: 1053241-01-2.mol

Synonyms:(S)-N,N-dimethyl-1-[2-(diphenylphosphanyl)-3-methoxyphenyl]ethylamine

Chemical Property of (S)-N,N-dimethyl-1-[2-(diphenylphosphanyl)-3-methoxyphenyl]ethylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-N,N-dimethyl-1-[2-(diphenylphosphanyl)-3-methoxyphenyl]ethylamine

There total 2 articles about (S)-N,N-dimethyl-1-[2-(diphenylphosphanyl)-3-methoxyphenyl]ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

chloro-diphenylphosphine (1079-66-9,74391-44-9) + S-(-)-[1-(3-methoxyphenyl)ethyl]-N,N-dimethylamine (889443-69-0) → (S)-N,N-dimethyl-1-[2-(diphenylphosphanyl)-3-methoxyphenyl]ethylamine (1053241-01-2)

Guidance literature:

S-(-)-[1-(3-methoxyphenyl)ethyl]-N,N-dimethylamine; With tert.-butyl lithium; In diethyl ether; pentane; at -50 ℃; for 24h;

chloro-diphenylphosphine; In diethyl ether; pentane; at 20 ℃; Further stages.;

DOI:10.1002/ejic.200700568

Reference yield:

sec.-butyllithium (598-30-1) + chloro-diphenylphosphine (1079-66-9,74391-44-9) + S-(-)-[1-(3-methoxyphenyl)ethyl]-N,N-dimethylamine (889443-69-0) → (S)-N,N-dimethyl-1-[2-(diphenylphosphanyl)-3-methoxyphenyl]ethylamine (1053241-01-2) + isobutyldiphenylphosphine (7650-79-5)

Guidance literature:

sec.-butyllithium; S-(-)-[1-(3-methoxyphenyl)ethyl]-N,N-dimethylamine; at -50 ℃; for 4h;

chloro-diphenylphosphine; at -50 - 20 ℃; Further stages. Title compound not separated from byproducts.;

DOI:10.1002/ejic.200700568

upstream raw materials:

sec.-butyllithium

chloro-diphenylphosphine

S-(-)-[1-(3-methoxyphenyl)ethyl]-N,N-dimethylamine