1-(2-O-acetyl-5-O-benzoyl-3-deoxy-β-D-ribofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine

Base Information

• Chemical Name: 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-β-D-ribofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine
• CAS No.: 220249-14-9
• Molecular Formula: C₂₀H₁₇Cl₂N₃O₅
• Molecular Weight: 450.278

Synonyms:1-(2-O-acetyl-5-O-benzoyl-3-deoxy-β-D-ribofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine

Chemical Property of 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-β-D-ribofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-β-D-ribofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine

There total 3 articles about 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-β-D-ribofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

4,6-dichloro-1H-imidazo<4,5-c>pyridine (2589-12-0) + (2S,3R,5S)-5-((benzoyloxy)methyl)tetrahydrofuran-2,3-diyl diacetate (90580-88-4) → 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-β-D-ribofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine (220249-14-9) + 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-α-D-ribofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine + 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-α-D-arabinofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine

Guidance literature:

With toluene-4-sulfonic acid; at 160 ℃; for 0.166667h; under 25 Torr;

DOI:10.1002/(SICI)1522-2675(19981216)81:12<2326::AID-HLCA2326>3.0.CO;2-4

Reference yield: 27.0%

4,6-dichloro-1H-imidazo<4,5-c>pyridine (2589-12-0) + (2S,3R,5S)-5-((benzoyloxy)methyl)tetrahydrofuran-2,3-diyl diacetate (90580-88-4) → 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-β-D-ribofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine (220249-14-9)

Guidance literature:

With tin(IV) chloride; In acetonitrile;

DOI:10.1081/NCN-100002486

Reference yield:

4,6-dichloro-1H-imidazo<4,5-c>pyridine (2589-12-0) + (2S,3R,5S)-5-((benzoyloxy)methyl)tetrahydrofuran-2,3-diyl diacetate (90580-88-4) → 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-β-D-ribofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine (220249-14-9) + 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-α-D-ribofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine + 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-α-D-arabinofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine + Benzoic acid (2S,4S,5R)-4-acetoxy-5-(4,6-dichloro-imidazo[4,5-c]pyridin-1-yl)-tetrahydro-furan-2-ylmethyl ester

Guidance literature:

With toluene-4-sulfonic acid; Heating;

DOI:10.1081/NCN-100002486

upstream raw materials:

4,6-dichloro-1H-imidazo<4,5-c>pyridine

(2S,3R,5S)-5-((benzoyloxy)methyl)tetrahydrofuran-2,3-diyl diacetate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 220249-14-9 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-β-D-ribofuranosyl)-4,6-dichloro-1H-imidazo<4,5-c>pyridine

Send

Send

Metric Ton KG G Pound L ML

Send

Send