5H-PYRROLO-[3,2-B:4,5-B']DIPYRIDINE

Base Information

• Chemical Name: 5H-PYRROLO-[3,2-B:4,5-B']DIPYRIDINE
• CAS No.: 75449-34-2
• Molecular Formula: C₁₀H₇N₃
• Molecular Weight: 169.186
• Mol file: 75449-34-2.mol

Synonyms:5H-pyrrolo<3,2-b:4,5-b'>dipyridine

Chemical Property of 5H-PYRROLO-[3,2-B:4,5-B']DIPYRIDINE

Chemical Property:

Purity/Quality:

5H-PYRROLO-[3,2-B:4,5-B']DIPYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5H-PYRROLO-[3,2-B:4,5-B']DIPYRIDINE

There total 8 articles about 5H-PYRROLO-[3,2-B:4,5-B']DIPYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

5H-Dipyrido[3,2-b;2',3'-d]pyrrole 1,9-dioxide (108349-61-7) → 5H-pyrrolo<3,2-b:4,5-b'>dipyridine (75449-34-2)

Guidance literature:

With titanium tetrachloride; tin(ll) chloride; In benzene; for 0.5h; Ambient temperature;

Reference yield: 55.0%

2-(3-nitropyridin-2-yl)pyridine (1069137-31-0) → 5H-pyrrolo<3,2-b:4,5-b'>dipyridine (75449-34-2)

Guidance literature:

With triphenylphosphine; In 1,2-dichloro-benzene; at 180 ℃; for 24h; Inert atmosphere;

Reference yield:

2,2'-bipyridine-3,3'-diamine (75449-26-2) → <2,2'-bipyridine>-3-hydroxylamine (105166-51-6) + 5H-pyrrolo<3,2-b:4,5-b'>dipyridine (75449-34-2) + [2,2'-bipyridine]-3,3'-diol (36145-03-6)

Guidance literature:

With hydrogenchloride; sodium nitrite; Yield given. Multistep reaction. Yields of byproduct given; 1.) 0-5 deg C, 15 min, 2.) 100 deg C, 0,5 h;

upstream raw materials:

5H-Dipyrido[3,2-b;2',3'-d]pyrrole 1,9-dioxide

2,2'-bipyridine-3,3'-diamine

2-(3-nitropyridin-2-yl)pyridine

2-Chloro-3-nitropyridine

Refernces

• 1、 Kaczmarek, Lukasz,Malinowski, Marek,Balicki, Roman. "SIMPLE AND EFFICIENT DEOXYGENATION OF HETEROAROMATIC N-OXIDES USING TiCl4/SnCl2.". . p. 787 - 790. Retrieved 2007/10/02.
• 2、 Kaczmarek, Lukasz. "Bipyridines. Part XVIII. On the Synthesis of -3-ol and Other Novel 2,2'-Bipyridine Derivatives from -3,3'-diamine". . p. 401 - 409. Retrieved 2007/10/02.