Technology Process of p-bromobenzyl isoclavulanate
There total 4 articles about p-bromobenzyl isoclavulanate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 70 percent / sodium hydroxide / H2O / 1.17 h / 0 °C
2: 69 percent / dimethylformamide / 1.5 h / Ambient temperature
3: 1.) H2, sodium hydrogen carbonate / palladium on carbon / 1.) ethanol, ambient temperature, 60 min, 2.) N,N-dimethylformamide, room temperature, 2 h
With
sodium hydroxide; hydrogen; sodium hydrogencarbonate;
palladium on activated charcoal;
In
water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 69 percent / dimethylformamide / 1.5 h / Ambient temperature
2: 1.) H2, sodium hydrogen carbonate / palladium on carbon / 1.) ethanol, ambient temperature, 60 min, 2.) N,N-dimethylformamide, room temperature, 2 h
With
hydrogen; sodium hydrogencarbonate;
palladium on activated charcoal;
In
N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 75 percent / ethanol / Ambient temperature
2: 70 percent / sodium hydroxide / H2O / 1.17 h / 0 °C
3: 69 percent / dimethylformamide / 1.5 h / Ambient temperature
4: 1.) H2, sodium hydrogen carbonate / palladium on carbon / 1.) ethanol, ambient temperature, 60 min, 2.) N,N-dimethylformamide, room temperature, 2 h
With
sodium hydroxide; hydrogen; sodium hydrogencarbonate;
palladium on activated charcoal;
In
ethanol; water; N,N-dimethyl-formamide;
