2-acetylphenyl isocyanate

Base Information

• Chemical Name: 2-acetylphenyl isocyanate
• CAS No.: 72500-32-4
• Molecular Formula: C₉H₇NO₃
• Molecular Weight: 177.159
• Mol file: 72500-32-4.mol

Synonyms:2-acetylphenyl isocyanate

Chemical Property of 2-acetylphenyl isocyanate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-acetylphenyl isocyanate

There total 5 articles about 2-acetylphenyl isocyanate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-acetylbenzoic acid azide (31385-27-0) → 2-acetylphenyl isocyanate (72500-32-4)

Guidance literature:

With benzene; durch Kochen;

Reference yield:

aspirin (50-78-2,98201-60-6) → 2-acetylphenyl isocyanate (72500-32-4)

Guidance literature:

Multi-step reaction with 3 steps

1: benzene; PCl₅

2: aqueous acetone; sodium azide

3: benzene / durch Kochen

With sodium azide; phosphorus pentachloride; acetone; benzene;

Reference yield:

O-acetylsalicyloyl chloride (5538-51-2) → 2-acetylphenyl isocyanate (72500-32-4)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. sodium azide / acetone / 24 h / 0 - 5 °C

2: benzene / 2 h / 70 - 75 °C

With sodium azide; In acetone; benzene;

DOI:10.1021/jm980600x

upstream raw materials:

2-acetylbenzoic acid azide

benzene

O-acetylsalicyloyl chloride

aspirin

Downstream raw materials:

2-methyl-1,3-benzoxazole