methyl 4,6-O-benzylidene-3-C-dichloromethyl-2-O-methyl-α-D-allopyranoside

Base Information

• Chemical Name: methyl 4,6-O-benzylidene-3-C-dichloromethyl-2-O-methyl-α-D-allopyranoside
• CAS No.: 161955-22-2
• Molecular Formula: C₁₆H₂₀Cl₂O₆
• Molecular Weight: 379.237
• Mol file: 161955-22-2.mol

Synonyms:methyl 4,6-O-benzylidene-3-C-dichloromethyl-2-O-methyl-α-D-allopyranoside

Chemical Property of methyl 4,6-O-benzylidene-3-C-dichloromethyl-2-O-methyl-α-D-allopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4,6-O-benzylidene-3-C-dichloromethyl-2-O-methyl-α-D-allopyranoside

There total 1 articles about methyl 4,6-O-benzylidene-3-C-dichloromethyl-2-O-methyl-α-D-allopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

4,6-O-benzylidene-2-O-methyl-α-D-ribo-hexopyranosid-3-ulose (23346-00-1) + (dichloromethyl)lithium (2146-67-0) → methyl 4,6-O-benzylidene-3-C-dichloromethyl-2-O-methyl-α-D-allopyranoside (161955-22-2)

Guidance literature:

DOI:10.1246/cl.1995.83

Reference yield: 80.0%

methyl 4,6-O-benzylidene-3-C-dichloromethyl-2-O-methyl-α-D-allopyranoside (161955-22-2) → (4aR,6S,7R,8R,8aR)-8-Hydroxy-6,7-dimethoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine-8-carbaldehyde

Guidance literature:

With tetra(n-butyl)ammonium hydroxide; In water; dimethyl sulfoxide; for 0.00833333h; Ambient temperature;

DOI:10.1016/0040-4039(96)00432-7

Reference yield: 78.0%

cesium acetate (3396-11-0) + methyl 4,6-O-benzylidene-3-C-dichloromethyl-2-O-methyl-α-D-allopyranoside (161955-22-2) → methyl 3-O-acetyl-4,6-O-benzylidene-3-C-formyl-2-O-methyl-α-D-glucopyranoside

Guidance literature:

With 18-crown-6 ether; In toluene; Heating;

DOI:10.1246/cl.1995.83

upstream raw materials:

4,6-O-benzylidene-2-O-methyl-α-D-ribo-hexopyranosid-3-ulose

(dichloromethyl)lithium

Downstream raw materials:

methyl 4,6-O-benzylidene-3-C-methyl-2-O-methyl-α-D-allopyranoside