Technology Process of C44H66O8Si
There total 1 articles about C44H66O8Si which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
triisopropylsilyl trifluoromethanesulfonate; C35H46O8;
With
pyridine;
In
1,4-dioxane;
at 20 ℃;
for 5h;
With
hydrogenchloride;
In
acetonitrile;
at 20 ℃;
for 0.333333h;
DOI:10.1021/ol0600741
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: H2 / Pd/C / ethanol / 11 h
2.1: 521 mg / imidazole / dimethylformamide / 16 h / 20 °C
3.1: KHMDS / tetrahydrofuran; toluene / 3 h / -78 °C
3.2: 88 percent / tetrahydrofuran; toluene / 3 h / -78 - -30 °C
4.1: 84 percent / CuI; n-PrNH2 / Pd(PPh3)4 / toluene / 0.5 h / 20 °C
5.1: 100 percent / TBAF / tetrahydrofuran / 11 h / 20 °C
With
1H-imidazole; propylamine; copper(l) iodide; tetrabutyl ammonium fluoride; hydrogen; potassium hexamethylsilazane;
palladium on activated charcoal; tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ol0600741
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: H2 / Pd/C / ethanol / 11 h
2.1: 521 mg / imidazole / dimethylformamide / 16 h / 20 °C
3.1: KHMDS / tetrahydrofuran; toluene / 3 h / -78 °C
3.2: 88 percent / tetrahydrofuran; toluene / 3 h / -78 - -30 °C
4.1: 84 percent / CuI; n-PrNH2 / Pd(PPh3)4 / toluene / 0.5 h / 20 °C
With
1H-imidazole; propylamine; copper(l) iodide; hydrogen; potassium hexamethylsilazane;
palladium on activated charcoal; tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ol0600741
