3-benzyloxycarbonylmethyl-1-[2-(1H-indol-3-yl)-ethyl]-pyridinium bromide

Base Information

• Chemical Name: 3-benzyloxycarbonylmethyl-1-[2-(1H-indol-3-yl)-ethyl]-pyridinium bromide
• CAS No.: 1358679-75-0
• Molecular Formula: Br*C₂₄H₂₃N₂O₂
• Molecular Weight: 451.363
• Mol file: 1358679-75-0.mol

Synonyms:3-benzyloxycarbonylmethyl-1-[2-(1H-indol-3-yl)-ethyl]-pyridinium bromide

Chemical Property of 3-benzyloxycarbonylmethyl-1-[2-(1H-indol-3-yl)-ethyl]-pyridinium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 3-benzyloxycarbonylmethyl-1-[2-(1H-indol-3-yl)-ethyl]-pyridinium bromide

There total 1 articles about 3-benzyloxycarbonylmethyl-1-[2-(1H-indol-3-yl)-ethyl]-pyridinium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

3-(2-bromoethyl)-1H-indole (3389-21-7) + pyridin-3-yl-acetic acid benzyl ester (170583-11-6) → 3-benzyloxycarbonylmethyl-1-[2-(1H-indol-3-yl)-ethyl]-pyridinium bromide (1358679-75-0)

Guidance literature:

at 80 ℃; for 3h; Inert atmosphere; Neat (no solvent);

DOI:10.1002/ejoc.201101058

Reference yield: 80.0%

3-benzyloxycarbonylmethyl-1-[2-(1H-indol-3-yl)-ethyl]-pyridinium bromide (1358679-75-0) → {1-[2-(1H-indol-3-yl)-ethyl]-1,2,5,6-tetrahydro-pyridin-3-yl}-acetic acid benzyl ester (1358679-56-7)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 20 ℃; for 20h; Inert atmosphere;

DOI:10.1002/ejoc.201101058

upstream raw materials:

3-(2-bromoethyl)-1H-indole

pyridin-3-yl-acetic acid benzyl ester

Downstream raw materials:

{1-[2-(1H-indol-3-yl)-ethyl]-1,2,5,6-tetrahydro-pyridin-3-yl}-acetic acid benzyl ester