1-(4-penthyphenyl)-2-(4-ethoxy-3-fluorophenyl)ethanol methoxymethyl ether

Base Information

• Chemical Name: 1-(4-penthyphenyl)-2-(4-ethoxy-3-fluorophenyl)ethanol methoxymethyl ether
• CAS No.: 940949-13-3
• Molecular Formula: C₂₃H₃₁FO₃
• Molecular Weight: 374.496
• Mol file: 940949-13-3.mol

Synonyms:1-(4-penthyphenyl)-2-(4-ethoxy-3-fluorophenyl)ethanol methoxymethyl ether

Chemical Property of 1-(4-penthyphenyl)-2-(4-ethoxy-3-fluorophenyl)ethanol methoxymethyl ether

Chemical Property:

Purity/Quality:

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Technology Process of 1-(4-penthyphenyl)-2-(4-ethoxy-3-fluorophenyl)ethanol methoxymethyl ether

There total 1 articles about 1-(4-penthyphenyl)-2-(4-ethoxy-3-fluorophenyl)ethanol methoxymethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

1-(4-penthyphenyl)-2-(4-ethoxy-3-fluorophenyl)ethanol (940949-12-2) + chloromethyl methyl ether (107-30-2) → 1-(4-penthyphenyl)-2-(4-ethoxy-3-fluorophenyl)ethanol methoxymethyl ether (940949-13-3)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃;

Reference yield: 34.0%

1-(4-penthyphenyl)-2-(4-ethoxy-3-fluorophenyl)ethanol methoxymethyl ether (940949-13-3) + carbon dioxide (124-38-9,18923-20-1) → 1-(4-penthyphenyl)-2-(4-ethoxy-2-carbooxy-3-fluorophenyl)ethanol methoxymethyl ether (940949-14-4)

Guidance literature:

1-(4-penthyphenyl)-2-(4-ethoxy-3-fluorophenyl)ethanol methoxymethyl ether; With sec.-butyllithium; In tetrahydrofuran; at -75 - -70 ℃; for 1h;

carbon dioxide; In tetrahydrofuran; at 20 ℃;

With hydrogenchloride; In tetrahydrofuran; water;

upstream raw materials:

1-(4-penthyphenyl)-2-(4-ethoxy-3-fluorophenyl)ethanol

chloromethyl methyl ether

Downstream raw materials:

1-(4-penthyphenyl)-2-(4-ethoxy-2-carbooxy-3-fluorophenyl)ethanol methoxymethyl ether