4-(4'-HYDROXY-3'-IODOPHENOXY)-3,5-DIIODO-BENZOIC ACID

Base Information

• Chemical Name: 4-(4'-HYDROXY-3'-IODOPHENOXY)-3,5-DIIODO-BENZOIC ACID
• CAS No.: 4618-45-5
• Molecular Formula: C₁₃H₇I₃O₄
• Molecular Weight: 607.91
• Hs Code.: 2918990090
• Mol file: 4618-45-5.mol

Synonyms:3,3',5-triiodothyroformic acid;

Chemical Property of 4-(4'-HYDROXY-3'-IODOPHENOXY)-3,5-DIIODO-BENZOIC ACID

Chemical Property:

• PSA: 66.76000
• LogP: 4.69650

Purity/Quality:

99%min ^*data from raw suppliers

4-(4'-HYDROXY-3'-IODOPHENOXY)-3,5-DIIODO-BENZOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4'-HYDROXY-3'-IODOPHENOXY)-3,5-DIIODO-BENZOIC ACID

There total 4 articles about 4-(4'-HYDROXY-3'-IODOPHENOXY)-3,5-DIIODO-BENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(4-hydroxy-phenoxy)-3,5-diiodo-benzoic acid (1838-55-7) → 3,3',5-triiodothyroformic acid (4618-45-5)

Guidance literature:

With ammonia; iodine;

Reference yield:

3,5-diiodo-4-(4-methoxy-phenoxy)-benzaldehyde (69240-57-9) → 3,3',5-triiodothyroformic acid (4618-45-5)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous KMnO₄; pyridine

2: aqueous HI

3: aqueous methanol. NH₃; iodine

With pyridine; potassium permanganate; ammonia; hydrogen iodide; iodine;

Reference yield:

3,5-diiodo-4-(4-methoxy-phenoxy)-benzoic acid (34043-77-1) → 3,3',5-triiodothyroformic acid (4618-45-5)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous HI

2: aqueous methanol. NH₃; iodine

With ammonia; hydrogen iodide; iodine;

upstream raw materials:

4-(4-hydroxy-phenoxy)-3,5-diiodo-benzoic acid

3,5-diiodo-4-(4-methoxy-phenoxy)-benzaldehyde

3,5-diiodo-4-(4-methoxy-phenoxy)-benzoic acid

Downstream raw materials:

4-(4-hydroxymethyl-2,6-diiodophenoxy)-2-iodo-phenol