CPI-444

Base Information

Chemical Name:CPI-444
CAS No.:443103-97-7
Molecular Formula:C₁₆H₁₂FN₅O
Molecular Weight:309.303
Hs Code.:

Synonyms:1-(2-fluorobenzyl)-4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine

Suppliers and Price of CPI-444

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
A2Areceptorantagonist1 98.25%
10mg
$ 190.00

ChemScene
A2Areceptorantagonist1 98.25%
5mg
$ 120.00

ChemScene
A2Areceptorantagonist1 98.25%
1mg
$ 80.00

ChemScene
A2Areceptorantagonist1 98.25%
100mg
$ 1350.00

ChemScene
A2Areceptorantagonist1 98.25%
50mg
$ 760.00

American Custom Chemicals Corporation
A2A RECEPTOR ANTAGONIST 1 95.00%
5MG
$ 458.04

AK Scientific
1-(2-fluorobenzyl)-4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine
500mg
$ 1506.80

AK Scientific
1-(2-fluorobenzyl)-4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine
100mg
$ 372.80

Total 5 raw suppliers

Chemical Property of CPI-444

Chemical Property:

Boiling Point:570.6±60.0 °C(Predicted)
PKA:3.17±0.10(Predicted)
Density:1.49±0.1 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

A2Areceptorantagonist1 98.25% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of CPI-444

There total 6 articles about CPI-444 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 446-48-0
o-fluorobenzyl bromide

: 443103-39-7
4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine

: 443103-97-7
1-(2-fluorobenzyl)-4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine

Guidance literature:: With NaH; In ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 443103-39-7
4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine

: 611-17-6
1-bromomethyl-2-chlorobenzene

: 443103-97-7
1-(2-fluorobenzyl)-4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine

Guidance literature:: 4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃;

1-bromomethyl-2-chlorobenzene; In N,N-dimethyl-formamide; at 20 ℃; Further stages.;
DOI:10.1016/j.bmcl.2008.03.072

Reference yield:

: 443106-98-7
tert-Butyl 6-amino-4-chloro-1H-pyrazolo[3,4-d]pyrimidine-1-carboxylate

: 443103-97-7
1-(2-fluorobenzyl)-4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine

Guidance literature:: Multi-step reaction with 3 steps

1: PdCl₂(PPh₃)2 / N,N-dimethyl-formamide

2: dimethyl amine / methanol; water

3: NaH / ethyl acetate; N,N-dimethyl-formamide

With NaH; dimethyl amine; PdCl₂(PPh₃)2; In methanol; water; ethyl acetate; N,N-dimethyl-formamide;