(1S,6S)-6-isopropenyl-3-methyl-2-cyclohexenyl (S)-O-methyl mandelate

Base Information

• Chemical Name: (1S,6S)-6-isopropenyl-3-methyl-2-cyclohexenyl (S)-O-methyl mandelate
• CAS No.: 115362-63-5
• Molecular Formula: C₁₉H₂₄O₃
• Molecular Weight: 300.398
• Mol file: 115362-63-5.mol

Synonyms:(1S,6S)-6-isopropenyl-3-methyl-2-cyclohexenyl (S)-O-methyl mandelate

Chemical Property of (1S,6S)-6-isopropenyl-3-methyl-2-cyclohexenyl (S)-O-methyl mandelate

Chemical Property:

Purity/Quality:

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Technology Process of (1S,6S)-6-isopropenyl-3-methyl-2-cyclohexenyl (S)-O-methyl mandelate

There total 2 articles about (1S,6S)-6-isopropenyl-3-methyl-2-cyclohexenyl (S)-O-methyl mandelate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3E,7Z)-3,7-dimethyl-2,5,6,9-tetrahydrooxonine (115306-96-2) → (S)-2-methoxy-2-phenylacetic acid (26164-26-1) + (1S,6S)-6-isopropenyl-3-methyl-2-cyclohexenyl (S)-O-methyl mandelate (115362-63-5)

Guidance literature:

With dmap; n-butyllithium; (1S,1'S)-bis(1-phenylethyl)amine; dicyclohexyl-carbodiimide; Multistep reaction; 1.) THF, hexane, RT, 36 h, 2.) RT, 2 h;

DOI:10.1021/jo00252a044

Reference yield:

(S)-2-methoxy-2-phenylacetic acid (26164-26-1) + (3E,7Z)-3,7-dimethyl-2,5,6,9-tetrahydrooxonine (115306-96-2) → (1R,6R)-6-isopropenyl-3-methyl-2-cyclohexenyl (S)-O-methyl mandelate (115306-98-4) + (1S,6S)-6-isopropenyl-3-methyl-2-cyclohexenyl (S)-O-methyl mandelate (115362-63-5)

Guidance literature:

With dmap; n-butyllithium; (1S,1'S)-bis(1-phenylethyl)amine; dicyclohexyl-carbodiimide; Multistep reaction; 1.) THF, hexane, RT, 36 h, 2.) RT, 2 h;

DOI:10.1021/jo00252a044

upstream raw materials:

(3E,7Z)-3,7-dimethyl-2,5,6,9-tetrahydrooxonine

(S)-2-methoxy-2-phenylacetic acid