(1'S,2'S,3S)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,3-dimethylheptanamide

Base Information

• Chemical Name: (1'S,2'S,3S)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,3-dimethylheptanamide
• CAS No.: 913962-59-1
• Molecular Formula: C₁₈H₂₉NO₂
• Molecular Weight: 291.434
• Mol file: 913962-59-1.mol

Synonyms:(1'S,2'S,3S)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,3-dimethylheptanamide

Chemical Property of (1'S,2'S,3S)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,3-dimethylheptanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1'S,2'S,3S)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,3-dimethylheptanamide

There total 1 articles about (1'S,2'S,3S)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,3-dimethylheptanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

n-butyllithium (109-72-8,29786-93-4) + E-(+)-(1'S,2'S)-N-methyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)but-2-enamide (678991-32-7) → (1'S,2'S,3R)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,3-dimethylheptanamide + (1'S,2'S,3S)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,3-dimethylheptanamide (913962-59-1)

Guidance literature:

With lithium fluoride; In tetrahydrofuran; hexane; at -105 - 20 ℃; Further Variations:; Solvents; Reagents; Reaction partners; Temperatures; reaction times; Product distribution;

DOI:10.1021/jo061205e

Reference yield: 88.0%

(1'S,2'S,3S)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,3-dimethylheptanamide (913962-59-1) → (-)-(S)-3-methylheptanoic acid (59614-85-6)

Guidance literature:

With sulfuric acid; In 1,4-dioxane; for 6h; Heating;

DOI:10.1021/jo061205e

Reference yield: 79.0%

(1'S,2'S,3S)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,3-dimethylheptanamide (913962-59-1) → (S)-3-methylheptan-1-ol (61169-84-4,1070-32-2,99427-18-6,111767-94-3)

Guidance literature:

With n-butyllithium; ammonia borane; diisopropylamine; In tetrahydrofuran; hexane; at 20 ℃; for 2h;

DOI:10.1021/jo061205e

upstream raw materials:

n-butyllithium

E-(+)-(1'S,2'S)-N-methyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)but-2-enamide

Downstream raw materials:

(S)-3-methylheptan-1-ol

(-)-(S)-3-methylheptanoic acid

(S)-(+)-14-Methyl-1-octadecene