Technology Process of 4'-benzenesulfonyl-3',5'-bis-O-(tert-butyldimethylsilyl)thymidine
There total 12 articles about 4'-benzenesulfonyl-3',5'-bis-O-(tert-butyldimethylsilyl)thymidine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
at 0 - 20 ℃;
for 5h;
optical yield given as %de;
DOI:10.1016/j.tet.2009.05.078
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tin(IV) chloride / dichloromethane / 1 h / -78 - -30 °C / Inert atmosphere
2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 5 h / 0 - 20 °C
With
tin(IV) chloride; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
DOI:10.1016/j.tet.2009.05.078
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tin(IV) chloride / dichloromethane / 1 h / -78 - -30 °C / Inert atmosphere
2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 5 h / 0 - 20 °C
With
tin(IV) chloride; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
DOI:10.1016/j.tet.2009.05.078