ethyl 3-(3-((((1R,2R,3S,4R)-4-(4-((2,4-dimethoxybenzyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl)methyl)amino)cyclobutyl)propanoate

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Chemical Name:ethyl 3-(3-((((1R,2R,3S,4R)-4-(4-((2,4-dimethoxybenzyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl)methyl)amino)cyclobutyl)propanoate
CAS No.:1380350-39-9
Molecular Formula:C₃₀H₄₁N₅O₆
Molecular Weight:567.685
Hs Code.:

ethyl 3-(3-((((1R,2R,3S,4R)-4-(4-((2,4-dimethoxybenzyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl)methyl)amino)cyclobutyl)propanoate

Synonyms:ethyl 3-(3-((((1R,2R,3S,4R)-4-(4-((2,4-dimethoxybenzyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl)methyl)amino)cyclobutyl)propanoate

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Chemical Property of ethyl 3-(3-((((1R,2R,3S,4R)-4-(4-((2,4-dimethoxybenzyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl)methyl)amino)cyclobutyl)propanoate

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Technology Process of ethyl 3-(3-((((1R,2R,3S,4R)-4-(4-((2,4-dimethoxybenzyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl)methyl)amino)cyclobutyl)propanoate

There total 3 articles about ethyl 3-(3-((((1R,2R,3S,4R)-4-(4-((2,4-dimethoxybenzyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl)methyl)amino)cyclobutyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1380290-31-2
ethyl 3-(3-oxocyclobutyl)propanoate

: (1S,2R,3R,5R)-3-(aminomethyl)-5-(4-((2,4-dimethoxybenzyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol

: 1380350-39-9
ethyl 3-(3-((((1R,2R,3S,4R)-4-(4-((2,4-dimethoxybenzyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl)methyl)amino)cyclobutyl)propanoate

Guidance literature:: With methanol; sodium tris(acetoxy)borohydride; acetic acid; In 1,2-dichloro-ethane; at 20 ℃;

Reference yield:

: 1968-40-7
ethyl 4-pentenoate

: 1380350-39-9
ethyl 3-(3-((((1R,2R,3S,4R)-4-(4-((2,4-dimethoxybenzyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl)methyl)amino)cyclobutyl)propanoate

Guidance literature:: Multi-step reaction with 3 steps

1: zinc/copper couple / diethyl ether / 72 h / 20 °C

2: zinc; ammonium chloride / methanol / 3 h / Reflux

3: sodium tris(acetoxy)borohydride; methanol / acetic acid / 1,2-dichloro-ethane / 20 °C

With methanol; zinc/copper couple; sodium tris(acetoxy)borohydride; ammonium chloride; zinc; acetic acid; In methanol; diethyl ether; 1,2-dichloro-ethane;

Reference yield:

: 1380291-29-1
ethyl 3-(2,2-dichloro-3-oxocyclobutyl)propanoate

: 1380350-39-9
ethyl 3-(3-((((1R,2R,3S,4R)-4-(4-((2,4-dimethoxybenzyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl)methyl)amino)cyclobutyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: zinc; ammonium chloride / methanol / 3 h / Reflux

2: sodium tris(acetoxy)borohydride; methanol / acetic acid / 1,2-dichloro-ethane / 20 °C

With methanol; sodium tris(acetoxy)borohydride; ammonium chloride; zinc; acetic acid; In methanol; 1,2-dichloro-ethane;