Multi-step reaction with 10 steps
1: 76 percent / propionic acid / xylene / 3 h / Heating
2: 100 percent / H2 / PtO2 / hexane / 30 h / 760 Torr
3: 6.7 g / LAH / diethyl ether / 0.5 h / Ambient temperature
4: 98 percent / imidazole / dimethylformamide / 1 h
5: 89 percent / 0.67 h / Heating
6: 50 percent / N-bromosuccinimide (NBS), aq. HClO4 / 1.5 h / 0 - 20 °C
7: 75 percent / Pb(OAc)4, CaCO3, I2 / cyclohexane / 3 h / Heating; Irradiation
8: 1.10 g / KOH / methanol / 0.5 h / Heating
9: 8 N Jones' reagent / acetone / 1 h / 0 °C
10: 62 percent / Zn, i-PrOH / dimethylformamide / 8 h / Heating
With
1H-imidazole; lead(IV) acetate; potassium hydroxide; N-Bromosuccinimide; lithium aluminium tetrahydride; perchloric acid; jones' reagent; hydrogen; iodine; propionic acid; isopropyl alcohol; calcium carbonate; zinc;
platinum(IV) oxide;
In
methanol; diethyl ether; hexane; cyclohexane; N,N-dimethyl-formamide; acetone; xylene;