1,2-O-isopropylidene-3-keto-5-O-benzyl-6-deoxy-6-C-vinyl-β-L-altrofuranose

Base Information

Chemical Name:1,2-O-isopropylidene-3-keto-5-O-benzyl-6-deoxy-6-C-vinyl-β-L-altrofuranose
CAS No.:1352234-53-7
Molecular Formula:C₁₈H₂₂O₅
Molecular Weight:318.37
Hs Code.:

Synonyms:1,2-O-isopropylidene-3-keto-5-O-benzyl-6-deoxy-6-C-vinyl-β-L-altrofuranose

Suppliers and Price of 1,2-O-isopropylidene-3-keto-5-O-benzyl-6-deoxy-6-C-vinyl-β-L-altrofuranose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,2-O-isopropylidene-3-keto-5-O-benzyl-6-deoxy-6-C-vinyl-β-L-altrofuranose

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,2-O-isopropylidene-3-keto-5-O-benzyl-6-deoxy-6-C-vinyl-β-L-altrofuranose

There total 9 articles about 1,2-O-isopropylidene-3-keto-5-O-benzyl-6-deoxy-6-C-vinyl-β-L-altrofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1352234-55-9
1,2-O-isopropylidene-5-O-benzyl-6-deoxy-6-C-vinyl-β-L-altrofuranose

: 1352234-53-7
1,2-O-isopropylidene-3-keto-5-O-benzyl-6-deoxy-6-C-vinyl-β-L-altrofuranose

Guidance literature:: With sodium acetate; pyridinium chlorochromate; In dichloromethane; at 0 - 23 ℃; for 6h; Molecular sieve;
DOI:10.1021/jo401166q

Reference yield:

: 1352234-51-5
1,2-O-isopropylidene-3-O-(2-naphthylmethyl)-β-L-arabinopentodialdofuranose

: 1352234-53-7
1,2-O-isopropylidene-3-keto-5-O-benzyl-6-deoxy-6-C-vinyl-β-L-altrofuranose

Guidance literature:: Multi-step reaction with 4 steps

1.1: magnesium bromide diethyl etherate / dichloromethane / 0.08 h / -78 °C

1.2: 3 h / 78 °C

2.1: sodium hydride; tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide; tetrahydrofuran; mineral oil / 2 h / 0 - 20 °C

3.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone; water / dichloromethane / 6 h / 23 °C

4.1: pyridinium chlorochromate; sodium acetate / dichloromethane / 6 h / 0 - 23 °C / Molecular sieve

With magnesium bromide diethyl etherate; water; sodium acetate; tetra-(n-butyl)ammonium iodide; sodium hydride; pyridinium chlorochromate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; mineral oil; 1.1: |Sakurai Allylation / 1.2: |Sakurai Allylation;
DOI:10.1021/jo401166q

Reference yield:

: 103763-12-8,103763-13-9
5-O-tert-butyldiphenylsilyl-α,β-L-arabinofuranose

: 1352234-53-7
1,2-O-isopropylidene-3-keto-5-O-benzyl-6-deoxy-6-C-vinyl-β-L-altrofuranose

Guidance literature:: Multi-step reaction with 8 steps

1.1: copper(II) sulfate; sulfuric acid / 1 h / 23 °C

2.1: sodium hydride; tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide; tetrahydrofuran; mineral oil / 2 h / 0 - 23 °C

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 23 °C

4.1: N-ethyl-N,N-diisopropylamine; sulfur trioxide pyridine complex / dimethyl sulfoxide; dichloromethane / 0.17 h / -20 °C

5.1: boron trifluoride diethyl etherate / dichloromethane / 0.08 h / -78 °C

5.2: 3 h / -78 °C

6.1: sodium hydride; tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide; tetrahydrofuran; mineral oil / 2 h / 0 - 20 °C

7.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone; water / dichloromethane / 6 h / 23 °C

8.1: pyridinium chlorochromate; sodium acetate / dichloromethane / 6 h / 0 - 23 °C / Molecular sieve

With sulfuric acid; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; water; sodium acetate; sulfur trioxide pyridine complex; tetra-(n-butyl)ammonium iodide; sodium hydride; copper(II) sulfate; N-ethyl-N,N-diisopropylamine; pyridinium chlorochromate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide; mineral oil; 4.1: |Parikh-Doering Oxidation / 5.1: |Sakurai Allylation / 5.2: |Sakurai Allylation;
DOI:10.1021/jo401166q