H 1702

Base Information

• Chemical Name: H 1702
• CAS No.: 38946-73-5
• Molecular Formula: C₉H₁₁N₅O₄
• Molecular Weight: 253.217
• Mol file: 38946-73-5.mol

Synonyms:

Chemical Property of H 1702

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of H 1702

There total 8 articles about H 1702 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

5-(6-amino-purin-9-ylmethyl)-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid (193410-07-0) → 4-(6-amino-purin-9-yl)-2,3-dihydroxy-butyric acid (38946-73-5,25486-40-2)

Guidance literature:

With acetic acid; at 65 ℃; for 4h;

DOI:10.1039/a707193k

Reference yield: 90.0%

L-eritadenine methyl ester (81691-57-8) → 4-(6-amino-purin-9-yl)-2,3-dihydroxy-butyric acid (38946-73-5,25486-40-2)

Guidance literature:

With sodium hydroxide; Ambient temperature;

DOI:10.1135/cccc19821392

Reference yield:

9-[(2S,3R,4R)-(5,4-dihydroxy-2,3-isopropylidenedioxy)pentyl]adenine (151359-36-3) → 4-(6-amino-purin-9-yl)-2,3-dihydroxy-butyric acid (38946-73-5,25486-40-2)

Guidance literature:

Multi-step reaction with 3 steps

1: NaIO₄ / H₂O / 1 h / 0 °C

2: 46 percent / O₂ / Pt/C / H₂O / 49 h / 45 °C

3: 10percent AcOH / 4 h / 65 °C

With sodium periodate; oxygen; acetic acid; platinum on activated charcoal; In water;

DOI:10.1055/s-1997-3273

upstream raw materials:

L-eritadenine methyl ester

2,3-O-cyclohexylidene-D-erythronolactone

adenine

5-(6-amino-purin-9-ylmethyl)-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid

Downstream raw materials:

9-(2S,3R)-erythro-(4-O-p-toluenesulfonyl-2,3-O-isopropylidene-2,3,4-trihydroxybutyl)adenine