SISOMICIN SULFATE

Base Information

• Chemical Name: SISOMICIN SULFATE
• CAS No.: 53179-09-2
• Molecular Formula: C₁₉H₃₇N₅O₇*H₂O₄S
• Molecular Weight: 545.612
• Hs Code.: 2941901010
• European Community (EC) Number: 258-414-4
• DSSTox Substance ID: DTXSID40860468
• Wikidata: Q105278062
• NCI Thesaurus Code: C84147
• ChEMBL ID: CHEMBL115339
• Mol file: 53179-09-2.mol

Synonyms:(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxy-cyclohexyl]oxy-5-methyl-4-methylamino-oxane-3,5-diol;32385-11-8;Salvamina;Sisomicine [INN-French];Sch-13475;Sisomycin;O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-4)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-6))-2-deoxy-L-streptamine;Prestwick_847;Siseptin (TN);D-Streptamine,O-3-deoxy-4-C-methyl-3- (methylamino)-a-L-arabinopyranosyl-(1f6)- O-[2,6-diamino-2,3,4,6-tetradeoxy-R-Dglycero- hex-4-enopyranosyl-(1f4)]-2-deoxy-,sulfate (2:5) (salt);Baymicine;Sisomicin sulfate [USAN:JAN];

Chemical Property of SISOMICIN SULFATE

Chemical Property:

• Melting Point: 70-73oC
• Boiling Point: 1504.5 °C at 760 mmHg
• Flash Point: 863.7 °C
• PSA: 842.34000
• LogP: 0.82120
• Storage Temp.: 2-8°C
• Solubility.: H2O: soluble50mg/mL
• Water Solubility.: Soluble in water
• XLogP3: -5.1
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 6
• Exact Mass: 447.26929854
• Heavy Atom Count: 31
• Complexity: 643

Purity/Quality:

≥98.0% ^*data from raw suppliers

Sisomicin sulfate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T,Xi
• Hazard Codes: T,Xi
• Statements: 61-20/21/22-36/37/38
• Safety Statements: 53-22-36/37/39-45-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1(COC(C(C1NC)O)OC2C(CC(C(C2O)OC3C(CC=C(O3)CN)N)N)N)O
• Uses: Sisomicin Sulfate Salt is an aminoglycoside antibiotic. It can also be used as reactant/reagent in structural and kinetics study of self-assembling macrocyclic dimer natural product aminoglycoside 66-40C and unnatural variants.
• Therapeutic Function: Antibiotic
• Clinical Use: Although Sisomycin Sulfate has been approved for human use in theUnited States, it has not been marketed in this country. Itsantibacterial potency and effectiveness against aminoglycoside-inactivating enzymes resemble those of gentamicin.Sisomicin also exhibits pharmacokinetics and pharmacologicalproperties similar to those of gentamicin.