N⁴-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-N²-(N-benzoylglycyl-L-threonyl)-L-asparaginyl-L-isoleucyl-L-serine amide

Base Information

• Chemical Name: N⁴-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-N²-(N-benzoylglycyl-L-threonyl)-L-asparaginyl-L-isoleucyl-L-serine amide
• CAS No.: 128154-48-3
• Molecular Formula: C₃₄H₅₂N₈O₁₄
• Molecular Weight: 796.832

Synonyms:N⁴-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-N²-(N-benzoylglycyl-L-threonyl)-L-asparaginyl-L-isoleucyl-L-serine amide

Chemical Property of N⁴-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-N²-(N-benzoylglycyl-L-threonyl)-L-asparaginyl-L-isoleucyl-L-serine amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N⁴-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-N²-(N-benzoylglycyl-L-threonyl)-L-asparaginyl-L-isoleucyl-L-serine amide

There total 6 articles about N⁴-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-N²-(N-benzoylglycyl-L-threonyl)-L-asparaginyl-L-isoleucyl-L-serine amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

N4-(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-N2-(N-benzoylglycyl-L-threonyl)-L-asparaginyl-L-isoleucyl-L-serine allyl ester (128154-58-5) → N4-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-N2-(N-benzoylglycyl-L-threonyl)-L-asparaginyl-L-isoleucyl-L-serine amide (128154-48-3)

Guidance literature:

With ammonia; In methanol; Ambient temperature;

DOI:10.1016/0008-6215(90)84107-6

Reference yield:

N4-(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-N2-L-asparagine allyl ester hydrochloride (118398-56-4) → N4-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-N2-(N-benzoylglycyl-L-threonyl)-L-asparaginyl-L-isoleucyl-L-serine amide (128154-48-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 18 percent / Et₃N, EEDQ / CHCl₃ / 168 h / Ambient temperature

2: 81 percent / EEDQ / CHCl₃

3: 86 percent / ammonia / methanol / Ambient temperature

With ammonia; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; triethylamine; In methanol; chloroform;

DOI:10.1016/0008-6215(90)84107-6

Reference yield:

N4-(2-Acetamino-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-N2-(tert-butoxycarbonyl)-asparagin-allylester (88224-28-6) → N4-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-N2-(N-benzoylglycyl-L-threonyl)-L-asparaginyl-L-isoleucyl-L-serine amide (128154-48-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 98 percent / HCl / CH₂Cl₂; diethyl ether / 3 h / Ambient temperature

2: 18 percent / Et₃N, EEDQ / CHCl₃ / 168 h / Ambient temperature

3: 81 percent / EEDQ / CHCl₃

4: 86 percent / ammonia / methanol / Ambient temperature

With hydrogenchloride; ammonia; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; triethylamine; In methanol; diethyl ether; dichloromethane; chloroform;

DOI:10.1016/0008-6215(90)84107-6

upstream raw materials:

N⁴-(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-N²-(N-benzoylglycyl-L-threonyl)-L-asparaginyl-L-isoleucyl-L-serine allyl ester

N-benzoylglycyl-L-threonine

L-Isoleucyl-L-serine allyl ester hydrochloride

N⁴-(2-Acetamino-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-N²-(tert-butoxycarbonyl)-asparagin-allylester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 128154-48-3 N⁴-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-N²-(N-benzoylglycyl-L-threonyl)-L-asparaginyl-L-isoleucyl-L-serine amide

Send

Send

Metric Ton KG G Pound L ML

Send

Send