tert-butyl 5-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)-N-(benzyloxycarbonyl)-L-norvalinate

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Chemical Name:tert-butyl 5-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)-N-(benzyloxycarbonyl)-L-norvalinate
CAS No.:1023328-06-4
Molecular Formula:C₃₃H₃₆Cl₂FN₅O₅
Molecular Weight:672.584
Hs Code.:

Synonyms:tert-butyl 5-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)-N-(benzyloxycarbonyl)-L-norvalinate

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Chemical Property of tert-butyl 5-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)-N-(benzyloxycarbonyl)-L-norvalinate

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Technology Process of tert-butyl 5-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)-N-(benzyloxycarbonyl)-L-norvalinate

There total 1 articles about tert-butyl 5-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)-N-(benzyloxycarbonyl)-L-norvalinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 756509-08-7
3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1H-pyrazol-4-yl)pyridin-2-amine

: 125050-17-1
(S)-tert-butyl 2-(benzyloxycarbonylamino)-5-bromopentanoate

: 1023328-06-4
tert-butyl 5-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)-N-(benzyloxycarbonyl)-L-norvalinate

Guidance literature:: 3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1H-pyrazol-4-yl)pyridin-2-amine; With 2-tert-butylimino-2-diethylamino-1,3-dimethyl-perhydro-1,3,2-diazaphosphorine; In acetonitrile; at 50 ℃; for 1h;

(S)-tert-butyl 2-(benzyloxycarbonylamino)-5-bromopentanoate; In acetonitrile; at 50 ℃; for 56h;